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Italy has its eye on its first European title in more than 50 years, and its next test comes Tuesday against Spain in the semifinals at Euro 2020. The Italians haven't hoisted the European trophy since 1968, but they have won every game at Euro 2020, from qualifying through the 2-1 quarterfinal win against Belgium. Spain is tied with Germany for the most Euro titles with three, beating Italy 4-0 in 2012 to win its most recent one. 

Kickoff is set for 3 p.m. ET at Wembley Stadium. William Hill Sportsbook lists Italy as the +140 favorite (risk $100 to win $140) on the 90-minute money line in its latest Italy vs. Spain odds, while Spain is the +220 underdog. The over-under for total goals scored is 2.5. Before you lock in any Spain vs. Italy picks, check out the Euro 2020 predictions and best bets from SportsLine's Martin Green.

After working in the sports betting industry for several years, Green became a professional sports writer and handicapper. Since then, his European soccer picks have been spot-on. Green has generated almost $19,000 for $100 bettors since the 2017-18 season. He's having a great Euro 2020 as well, with his picks generating well over $1,100 in profit for $100 bettors through the quarterfinals. Green has his finger on the pulse of the game all over the globe.

Now, Green has taken an in-depth look at Italy vs. Spain at Euro 2020 and locked in his best bets. You can head to SportsLine now to see his picks. Here are the betting lines and trends for Spain vs. Italy:

  • Italy vs. Spain spread: Italy -0.5
  • Italy vs. Spain over-under: 2.5 goals
  • Italy vs. Spain money line: Italy +140, Spain +220, Draw +210
  • ESP: Ferran Torres, 21, has eight goals in 16 matches with the national team
  • ITA: Goalkeeper Gianluigi Donnarumma has 18 clean sheets in 31 international starts

Why you should back Italy

The Azzurri have been on a mission since failing to qualify for the 2018 World Cup, and they have lost just twice since manager Roberto Mancini took over in May 2018. The last loss was in September of that year, a 1-0 setback to Portugal, and the win against world No. 1 Belgium ran Italy's unbeaten streak to 32. Italy has scored in all but two of those games and posted a clean sheet in 23. It has outscored its opponents 11-2 since the start of the Euro 2020 group stage, and a defense led by Juventus veterans Giorgio Chiellini and Leonardo Bonucci has been impenetrable.

Goalkeeper Gianluigi Donnarumma is just 22 but is one of the best in the world, and he tied for the Serie A lead with 14 clean sheets last season with AC Milan. The attack is led by midfielders Nicolo Barella and Marco Verratti, who have a combined 11 goals and five assists in the team's last 14 matches. The pace of Ciro Immobile and Lorenzo Insigne up front could cause problems for a Spanish defense that was under intense pressure through extra time in consecutive matches. Immobile scored 25 goals with Lazio last season, while Insigne had 19 with Napoli. 

Why you should back Spain

Spain has not lost in 13 games (6-7-0), and while La Roja has been uninspired at times, they've scored at least five goals in three of those. It handed Germany its worst loss since 1931 when Ferran Torres put up a hat trick in a 6-0 victory in a November Nations League match, and it has 11 goals in its past three games at Euro 2020. Spain is 7-5-2 in the last 14 meetings with Italy, including a 4-0 victory in the 2012 final to win its last Euro title. The Spaniards also should be motivated as they move closer to winning their record fourth European championship to break a tie with Germany.

Torres, Alvaro Morata and Gerard Moreno are all capable scorers up top, and the team is inspired by captain Sergio Busquets, who dictates play from his midfield spot. Spain leads the tournament in possession time (67 percent), pass completion (89.4) and shots on target (39). The 5-3 win against Croatia was the only time during its unbeaten run that it allowed multiple goals. The defense is led by Aymeric Laporte and Pau Torres in the middle, and goalkeeper Unai Simon is brimming with confidence after his huge saves in the shootout with Switzerland.

How to make Spain vs. Italy Euro 2020 picks

Green has analyzed Italy vs. Spain from every possible angle. He leaning over on the goal total (2.5), and he has locked in two best bets. He's only sharing those picks on SportsLine.

So who wins Italy vs. Spain? And where does all the betting value lie? Visit SportsLine now to see the best bets for Spain vs. Italy, all from the European soccer expert who has generated nearly $19,000 for $100 bettors since the 2017-18 season.