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Rafael Nadal has never lost in the French Open semifinals, a streak that will be put to the test Friday against Diego Schwartzman in Paris. The much-anticipated match begins at 8:50 a.m. ET from Stade Roland Garros. Schwartzman stunned Nadal in a straight-sets win last month in Rome, giving the 28-year-old Argentinian confidence he can take down the clay master again Friday. That is Schwartzman's only win in 10 tries against Nadal.

Aiming for his 13th French Open singles title, Nadal is a -700 favorite (risk $700 to win $100) in the latest Nadal vs. Schwartzman odds from William Hill, with Schwartzman getting +450 (risk $100 to win $450) as the underdog. William Hill set the over-under for total games at 33.5, with Nadal favored by 7.5 games. Before making any 2020 French Open picks, be sure to see the latest tennis predictions from SportsLine's Sean Calvert

Calvert is the famed handicapper who took down a huge score on Dominic Thiem winning Indian Wells at 80-1 last year, among many stunning calls. He's racked up seven straight profitable seasons betting tennis. 

At Wimbledon last year, Calvert told his followers to grab 3-1 odds on Novak Djokovic facing Roger Federer in the final, adding Djokovic would win it all. The result: Djokovic and Federer cruised into the finals, with Djokovic winning the longest men's singles final in tournament history. Anyone who followed Calvert's advice was handsomely rewarded.

Now, Calvert has locked in on the 2020 French Open men's semifinal matchup featuring Nadal vs. Schwartzman and revealed his best bets. Head to SportsLine to see them.

Top Nadal vs. Schwartzman predictions

For the 2020 French Open semifinals, Calvert likes Schwartzman to win at least one set at -120 (risk $120 to win $100). He believes the ball and the conditions will be big factors.

"In the past, Nadal has had things by and large just how he likes them in Paris in the early summer, with sunshine, dry courts and (crucially) Babolat balls that take a lot more of his heavy topspin than this year's new Wilson ones do," Calvert said.

"It was telling pre-tournament that both Nadal and Dominic Thiem, who both use tons of topspin, were bemoaning the loss of the Babolat ball."

"Stats have shown that Nadal's ball is some way down from his norm in terms of the height it reaches off the court this fortnight, which was always going to be the case playing on damp courts and with a Wilson ball in cold conditions."

How to make Nadal vs. Schwartzman picks

In addition to backing Schwartzman to win a set, Calvert has released two other strong bets: the outright winner and whether the match goes over or under 33.5 games. Be sure to see Calvert's picks and analysis before locking in your French Open picks 2020 for the men's semifinals. 

Who wins Nadal vs. Schwartzman in the French Open 2020 men's semifinal? And what other pick could lead to a big return? Visit SportsLine now to see Sean Calvert's best bets for Nadal vs. Schwartzman, all from the famed tennis handicapper who's had seven straight profitable seasons.