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Players reaching new heights meet when Cori "Coco" Gauff takes on Barbora Krejcikova in a quarterfinal match of the 2021 French Open on Wednesday at 5 a.m. ET. Gauff has rolled through all four of her opponents in straight sets, including a 6-3, 6-1 win over Ons Jabeur in the fourth round. Krejcikova, after winning a three-set first-round matchup, has also cruised into the quarterfinals, including a 6-2, 6-0 win over Sloane Stephens in the fourth round. 

The latest Gauff vs. Krejcikova odds from William Hill Sportsbook list Gauff at -125 on the money line (risk $125 to win $100), while Krejcikova is the underdog at +100. The over-under for total games is set at 21.5 in the 2021 French Open odds. Before making any Krejcikova vs. Gauff picks, see the 2021 French Open predictions from elite tennis handicapper Gavin Mair.

A renowned women's tennis handicapper, Mair cashed in huge at last year's French Open. He picked Iga Swiatek to win (-163) and win in straight sets (+140), and he was right on both counts.

He also called unseeded Jelena Ostapenko (80-1) winning the 2017 French Open, Naomi Osaka (32-1) winning the 2018 U.S. Open and Bianca Andreescu (20-1) winning the 2019 U.S. Open.

Now, Mair has broken down the latest 2021 French Open odds from William Hill and released a pair of best bets for this matchup. Head to SportsLine to see them.

Coco Gauff vs. Barbora Krejcikova preview

Mair has tracked the rise of both players, who are coming off singles titles in warm-up events leading into the Open. Gauff, 17, is already entering her third year of women's competition with a pair of titles and a ranking of No. 25. Krejcikova, 25, is a seasoned veteran, making her WTA Tour debut in 2014, and is ranked No. 33.

Krejcikova has been busy this year, and reached the final of a WTA 1000 event for the first time. She later teamed up with Katerina Siniakova to win a doubles title at the Madrid Open and followed that up with a women's singles title at the Internationaux de Strasbourg. She defeated Sorana Cirstea in the final.

The tennis expert knows Krejcikova's baseline style has allowed her to be a bully on the court and that was evident in the past two rounds of the French Open 2021. In the third round, she clobbered Elina Svitolina 6-3, 6-2. She followed that up with a tidy 67-minute win over Stephens.

Gauff has been dominant in the tournament and Mair sees her being able to go toe-to-toe with Krejcikova. Gauff defeated Aleksandra Krunic and Wang Qiang before receiving a walkover over 13th-seeded Jennifer Brady. She then needed just 53 minutes to defeat Ons Jabeur to reach the quarterfinals.

How to make Krejcikova vs. Gauff picks

Not only does Mair have a strong pick on the winner, he also loves a prop bet that brings a big plus-money return. Be sure to see Mair's picks and analysis before locking in your 2021 French Open picks.

Who wins Gauff vs. Krejcikova in the French Open 2021? And which prop bet bring a big return? Visit SportsLine right now to see Gavin Mair's best bets, all from the acclaimed expert who has owned this tournament.