Robert Deutsch / USA TODAY Sports

In a tournament featuring surprising results up and down the draw, the men's semifinals in the 2021 Miami Open conclude with Andrey Rublev taking on Hubert Hurkacz in the second match of the day on Friday. Rublev, the No. 4 seed, toppled only one seeded player on the way to the semifinals. Hurkacz, the No. 26 seed, needed three consecutive seed-line upsets to reach the semifinal round.

The semifinal match is scheduled to begin at approximately 7 p.m. ET in Miami. William Hill Sportsbook lists Rublev as a -400 favorite (risk $400 to win $100), while Hurkacz is listed at +300 in the latest Rublev vs. Hurkacz odds. William Hill offers a variety of other wagers, with the over-under for total games set at 22.5 in the latest 2021 Miami Open odds. Before finalizing any Hurkacz vs. Rublev picks, be sure to see the 2021 Miami Open predictions from elite tennis handicapper Sean Calvert.

Calvert is the famed handicapper who called John Isner winning the 2018 Miami Open at 100-1. In 2019, Calvert took down a huge score on Dominic Thiem winning Indian Wells at 80-1, among many stunning calls. Anybody who followed his advice cashed a huge winner. 

Now, Calvert has broken down the latest 2021 Miami Open men's semifinal odds and released his coveted best bets for Rublev vs. Hurkacz. He's sharing his picks and analysis at SportsLine.

Andrey Rublev vs. Hubert Hurkacz preview

Hurkacz is red-hot after a trio of impressive wins, toppling highly ranked players in Denis Shapovalov, Milos Raonic and Stefanos Tsitsipas. He produced 39 winners in the quarterfinals and showed resilience in pulling off a comeback win after dropping the opening set. 

Hurkacz also served well in the last round, generating 15 aces against just one double fault, and he is averaging 10.8 aces per match in the tournament. He also defeated Rublev in three sets at the 2020 Rome Masters, and that was the only previous matchup between the two players.

Rublev is the only semifinalist who hasn't lost a set in the tournament. He is 15-3 on hard courts in 2021, and he has been wildly impressive in pivotal points. At the age of 23, this is his first Masters 1000 semifinal. However, Rublev is the highest seeded player remaining in the tournament and the only player currently ranked in the top 10 in the world that is still alive in the field.

How to make Hurkacz vs. Rublev picks

Calvert likes the over 22.5 total games, and he's also revealed two other best bets, including one that pays out over 2-1. Be sure to see Calvert's picks and analysis before making your Miami Open 2021 picks.

Who wins Hurkacz vs. Rublev? And which prop returns more than 2-1? Visit SportsLine now to see Calvert's best bets for Rublev vs. Hurkacz, all from the acclaimed expert who called John Isner winning the 2018 Miami Open at 100-1