Top-15 players looking to reach their first Grand Slam championship meet when No. 4 Aryna Sabalenka of Belarus faces No. 13 Karolina Pliskova of the Czech Republic in a 2021 Wimbledon women's singles semifinal match on Thursday at approximately 9:45 a.m. ET. The two have met twice before with Sabalenka winning both times. Sabalenka defeated Pliskova 2-6, 6-3, 7-5 in the second round of the Cincinnati Open in August 2018. She also earned a 6-3, 2-6, 7-6 (5) victory in the quarterfinals of the Eastbourne Open in June 2018.

William Hill Sportsbook lists Sabalenka as the -225 favorite (risk $225 to win $100) on the money line, while Pliskova is a +175 underdog in the latest Sabalenka vs. Pliskova odds. Other 2021 Wimbledon odds of note for this matchup include the game total lat 21.5 and Sabalenka at -3.5 for game handicap betting. Before making any Pliskova vs. Sabalenka picks, you need to see the Wimbledon 2021 predictions from SportsLine's tennis expert Gavin Mair.

A renowned women's tennis handicapper, he cashed in huge at the 2020 French Open. Mair picked Iga Swiatek to win (-163) and win in straight sets (+140), and he was right on both counts. 

He also called unseeded Jelena Ostapenko (80-1) winning the 2017 French Open, Naomi Osaka (32-1) winning the 2018 U.S. Open and Bianca Andreescu (20-1) winning the 2019 U.S. Open.

Now, Mair has broken down the latest Wimbledon 2021 odds and released his coveted best bets for Pliskova vs. Sabalenka picks. He's sharing all of his Wimbledon picks and tennis analysis only at SportsLine.

Aryna Sabalenka vs. Karolina Pliskova preview 

Mair has enjoyed watching the progression of each player's career and expects a competitive match. Pliskova, 29, who turned pro in 2009, has won 16 career singles titles and reached No. 1 in the rankings in July of 2017. She has reached the semifinals of a Grand Slam tournament for the third time, reaching the finals of the U.S. Open in 2016. She is 561-307 in her singles career.

She has been on a roll at Wimbledon 2021, winning all five matches in straight sets, including a 6-2, 6-2 win over Switzerland's Viktorija Golubic on Tuesday in the quarterfinals. Her previous-best tournament this year was at Rome in May when she reached the finals, losing 6-0, 6-0 to Poland's Iga Swiatek, who is ranked ninth in the world. Pliskova has played well on grass, posting a 5-2 mark this year. She is 57-26 on grass in her career.

Sabalenka has also had a solid season, compiling a 34-10 record, including a 7-2 mark on grass. In the warm-up tournament to Wimbledon at Eastbourne last month, she reached the quarterfinals where she lost a hard-fought 7-6, 0-6, 6-4 decision to Camila Giorgi of Italy. Sabalenka has wins at Abu Dhabi and Madrid and a runner-up finish at Stuttgart this year.

The 23-year-old has played exclusively in the WTA Tour since 2018. A year later, she debuted in the top 10 in the rankings, but finished the season ranked No. 11. In 2020, she earned three WTA titles and entered this year on a nine-match winning streak. She reached the third round of the French Open and fourth round of the Australian Open in 2021. 

How to make Pliskova vs. Sabalenka picks

Mair has revealed his full breakdown and has locked in a best bet that returns plus-money. Be sure to check out Mair's expert analysis before making your Wimbledon 2021 picks for the women's semifinals.

So who wins Sabalenka vs. Pliskova? And what pick could lead to a big return? Visit SportsLine now to see Gavin Mair's bets for the 2021 Wimbledon semifinals, all from the tennis expert who has called long shot winners of three grand slam women's titles since 2017, and find out.