Tennis: Wimbledon
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The 2022 U.S. Open will begin Monday at 11 a.m. ET, and all eyes will be on Serena Williams, at least in the early going. The 40-year-old will bow out after the Grand Slam tournament that has been a special part of her storied career. She won the first of her 23 Grand Slam titles at Flushing Meadows in 1999 and went on to win the U.S. Open five more times, most recently in 2014. While she's a longshot to contend, she will soak in the adoration of the crowd and watch the players she influenced during her dominant run. The top U.S. Open 2022 women's contenders include world No. 1 Iga Swiatek and reigning champion Emma Raducanu, among many others. Sloane Stephens (2017) was the first American aside from Serena and Venus Williams to win the Open since 1998, and the sisters are both longshots this time around. The likes of Coco Gauff, Jessica Pegula and Madison Keys have a chance to become the second.

Swiatek is the +350 favorite (risk $100 to win $350) in Caesars Sportsbook's latest 2022 U.S. Open women's odds, followed by Simona Halep (+750) and Gauff (+1400). Raducanu (+2000), Naomi Osaka (+2000) and Pegula (+2500) also are expected to contend. Keys (+3500) and Stephens (+6500) are longer shots, along with Serena Williams (+5000). Venus Williams is among the longest shots in the draw at +30000. Before making any tennis picks on the 2022 U.S. Open, you need to see who tennis expert Jose Onorato is backing.

Onorato grew up playing competitive tennis in Caracas, Venezuela. After coming to the U.S., he trained with famed coach Nick Bollettieri at IMG Academy in Florida and faced players like Robert Farah, now one of the world's top-ranked doubles players.

Onorato, who holds dual degrees in finance and economics from the University of Miami, does extensive research before placing any tennis bet. He studies current form, players' tendencies on a particular surface, weather conditions and many other relevant factors. That systematic approach helped Onorato go 69-46 -- up 54.98 units -- from January through July.

Now, Onorato has broken down the latest U.S. Open 2022 odds and released his coveted best bets to win it all. Head to SportsLine to see them.

Top 2022 U.S. Open women's predictions

One surprising pick from Onorato is that he is fading world No. 1 Swiatek, the tournament favorite at Caesars. She has won two Grand Slams over the past two years and has the best record on tour this year. She is 28-5 on hard courts and won three straight tournaments on the surface as part of a dominant 37-match win streak. That run also included her second French Open title. She was sent packing in the third round at Wimbledon and hasn't been the same since.

In the three tournaments since her loss at the All-England Club, the Polish star has lost in the third round twice and in a quarterfinal. She was beaten by Madison Keys in Cincinnati and by 15th-ranked Beatriz Haddad Maia in Toronto. She has some big hitters on her side of the draw and could face a tough battle with Sloane Stephens in the second round. In what is looking like a tournament that could be won by about a dozen players, the expert is looking for better value. See who he is backing right here.

Top 2022 U.S. Open women's picks

Instead, Onorato is backing an underdog who would pay off at more than 20-1. This player has been trending upward since the start of the season and has beaten several top-10 players. She is a dark horse to pull off a stunning result in Flushing Meadows. You really need to see his picks and analysis at SportsLine before making any 2022 U.S. Open bets.

So who wins the 2022 U.S. Open women's singles title? And which long shot could make a serious run at the Grand Slam trophy? Visit SportsLine now to see Jose Onorato's bets for the 2022 U.S. Open, all from the tennis expert who knows the game from a player's perspective.