For Serena Williams, the fourth time was the charm.

After losses in three straight majors, Williams defeated No. 4 Angelique Kerber on Saturday, 7-5, 6-3, to win Wimbledon and tie Steffi Graf for the most career Open-era Grand Slam wins with 22.

"I had a couple of tries this year, I lost to two great opponents -- one of them actually being Angelique," Williams said after the match. "It makes the victory even sweeter to know how hard I worked for it."

It was also the seventh Wimbledon victory for the 34-year-old, which ties her with Graf for second all-time behind Martina Navratilova's nine.

"This court definitely feels like home," said Williams.

Kerber and Williams put together a plethora of brilliant rallies throughout the match, but in the end Williams' serve was just too strong. At one point she went 30 straight service games without facing a break point during the tournament.

Serena Williams won Wimbledon, tying an Open-era record for career Grand Slam wins. Getty Images

Williams had revenge on the mind after losing to Kerber in January's Australian Open final.

"I love playing her," Williams said after the Wimbledon final. "She's such a great opponent. She really brings out great tennis in me."

Kerber faced a tall task, having already beaten Venus Williams in the semifinal -- no player has ever beaten both Williams sisters in the same Wimbledon tournament.

The players went back and forth in the first set, with no service breaks for the first 11 games. But at 6-5, Williams finally got her break to take the set and gain the momentum.

The second set was much of the same, with both players holding serve until Williams came up with a huge break to take a 5-3 lead. She then served to close out the match and make history.

Williams will have an opportunity to break Graf's record at the U.S. Open, which begins at the end of August.