Love and Wayne Ellington hit three consecutive late 3-pointers to give the Timberwolves the lead for good.
Love was 12 of 17 from the field, hitting three 3-pointers. Ellington added 22 points on 8-of-11 shooting and also made three 3-pointers.
"We showed our youth a little down the stretch with them coming back a couple times," Love said, "but we also showed that in these situations we can win."
Bucks center Andrew Bogut made his first game appearance since dislocating his right elbow, spraining his wrist and breaking his hand April 3 against Phoenix when he fell after a dunk.
The 7-foot Australian - wearing a brace on his elbow and a glove on his hand - had 11 points and five rebounds and four fouls in 14 minutes after missing the Bucks' loss Saturday night in Memohis because of a migraine headache.
"It was great," teammate Chris Douglas-Roberts said. "He definitely has a presence out there if he's scoring or not."
Reserve forward Ersan Ilyasova led the Bucks (3-3) with 22 points. He missed a 3-point try from the right corner with 10 seconds left that would have tied the game.
Carlos Delfino added 19 points and had four 3-pointers, three in the first quarter.
The game was played at Sioux Falls Arena, the home of the Timberwolves' NBA D-League affiliate. Minnesota is 5-1 in preseason appearances in Sioux Falls. ... Luke Ridnour started at point guard for Minnesota. He spent the previous two seasons with the Bucks, averaging 10.4 points and 4.0 assists in 2009-10.