| Last updated: Sat, November 21, 2009, 17:43 EST |
| Friday, November 20, 2009 |
| Team | Player | Transaction |
| Buffalo Bills | Keith Ellison | Placed on IR, quadricep |
| Buffalo Bills | Cary Harris | Activated from the Practice Squad |
| Chicago Bears | Garrett Wolfe | Placed on IR, lacerated kidney |
| Chicago Bears | Kahlil Bell | Activated from the Practice Squad |
| Detroit Lions | Eric Fowler | Activated from the Practice Squad |
| Detroit Lions | Stephen Peterman | Placed on IR, right ankle |
| Thursday, November 19, 2009 |
| Team | Player | Transaction |
| Buffalo Bills | Brian Brohm | Activated from the Practice Squad |
| Buffalo Bills | Gibran Hamdan | cut |
| Chicago Bears | Joe Clermond | practice squad addition |
| Green Bay Packers | Mike Reilly | practice squad addition |
| Houston Texans | Jesse Nading | practice squad addition |
| San Diego Chargers | Gerald Cadogan | practice squad addition |
| Tampa Bay Buccaneers | Darnell Jenkins | practice squad addition |
| Wednesday, November 18, 2009 |
| Team | Player | Transaction |
| Atlanta Falcons | Troy Bergeron | practice squad addition |
| Baltimore Ravens | Marcus Paschal | practice squad addition |
| Baltimore Ravens | K.J. Gerard | Activated from the Practice Squad |
| Baltimore Ravens | Billy Cundiff | signed |
| Baltimore Ravens | Haruki Nakamura | Placed on IR, ankle |
| Buffalo Bills | Christian Gaddis | practice squad addition |
| Buffalo Bills | C.J. Hawthorne | practice squad deletion |
| Buffalo Bills | Derek Fine | Placed on IR, knee |
| Cleveland Browns | Arnold Harrison | acquired from waivers |
| Cleveland Browns | Dave Zastudil | Placed on IR, right knee |
| Cleveland Browns | Chris Williams | practice squad deletion |
| Cleveland Browns | James Robinson | practice squad addition |
| Cleveland Browns | Jake Allen | acquired from waivers |
| Cleveland Browns | Steve Heiden | Placed on IR, knee |
| Detroit Lions | DeAngelo Smith | signed |
| Detroit Lions | Marquand Manuel | Placed on IR, shoulder |
| Jacksonville Jaguars | Nate Swift | practice squad addition |
| Miami Dolphins | Ronnie Brown | Placed on IR, foot |
| Miami Dolphins | Nate Ness | Activated from the Practice Squad |
| San Diego Chargers | Corey Clark | Activated from the Practice Squad |
| San Diego Chargers | Jyles Tucker | Placed on IR, ankle |
| Tuesday, November 17, 2009 |
| Team | Player | Transaction |
| Baltimore Ravens | Steven Hauschka | cut |
| Buffalo Bills | Joe Klopfenstein | signed |
| Carolina Panthers | Jason Pociask | practice squad deletion |
| Carolina Panthers | Jordan Gross | Placed on IR, right ankle |
| Carolina Panthers | Brian De La Puente | practice squad addition |
| Carolina Panthers | Eric Moore | practice squad addition |
| Carolina Panthers | Charly Martin | Activated from the Practice Squad |
| Cincinnati Bengals | Larry Johnson | signed |
| Cincinnati Bengals | Ben Utecht | Taken off IR, severe concussion |
| Cincinnati Bengals | Antonio Chatman | cut |
| Cincinnati Bengals | Ben Utecht | cut |
| Cincinnati Bengals | Brannon Condren | practice squad addition |
| Cincinnati Bengals | Antonio Chatman | Taken off IR, ankle |
| Cincinnati Bengals | Orien Harris | cut |
| Detroit Lions | Jack Williams | Placed on IR, torn ACL |
| Detroit Lions | Melvin Fowler | signed |
| Green Bay Packers | Jake Allen | cut |
| Houston Texans | Arian Foster | Activated from the Practice Squad |
| Houston Texans | Jesse Nading | cut |
| Indianapolis Colts | Colin Cloherty | practice squad deletion |
| Jacksonville Jaguars | Nate Hughes | Activated from the Practice Squad |
| Jacksonville Jaguars | Jarett Dillard | Placed on IR, broken ankle |
| Kansas City Chiefs | Tim Castille | signed |
| Kansas City Chiefs | Dwayne Bowe | suspended, 4 games (policy on banned substances) |
| New England Patriots | Adrian Grady | practice squad addition |
| New Orleans Saints | Chris McAlister | signed |
| New Orleans Saints | Chase Daniel | cut |
| New York Jets | Britt Davis | practice squad addition |
| Pittsburgh Steelers | Curtis Gatewood | practice squad addition |
| Pittsburgh Steelers | Donovan Woods | Activated from the Practice Squad |
| Pittsburgh Steelers | Arnold Harrison | cut |
| Seattle Seahawks | Xavier Omon | practice squad addition |
| Seattle Seahawks | Devin Moore | practice squad deletion |
| St. Louis Rams | Jordan Kent | signed |
| Tampa Bay Buccaneers | Maurice Evans | practice squad deletion |
| Tampa Bay Buccaneers | Arron Sears | Activated from the physically unable to perform list |
| Tennessee Titans | Fernando Velasco | practice squad addition |
| Washington Redskins | Doug Dutch | practice squad addition |
| Monday, November 16, 2009 |
| Team | Player | Transaction |
| Atlanta Falcons | Troy Bergeron | cut |
| Atlanta Falcons | Aaron Stecker | signed |
| New York Jets | Ahmad Carroll | cut |
| New York Jets | Kenwin Cummings | Activated from the Practice Squad |
| St. Louis Rams | Keenan Burton | Placed on IR, torn patellar tendon |
| Sunday, November 15, 2009 |
| Team | Player | Transaction |
| Cleveland Browns | Reggie Hodges | signed |
| New England Patriots | Isaiah Stanback | Activated from the Practice Squad |
| New England Patriots | Brandon Tate | Placed on IR, knee |
| Saturday, November 14, 2009 |
| Team | Player | Transaction |
| Atlanta Falcons | Aaron Stecker | cut |
| Atlanta Falcons | Troy Bergeron | Activated from the Practice Squad |
| Miami Dolphins | Kory Sperry | Activated from the Practice Squad |
| Miami Dolphins | J.D. Folsom | practice squad addition |
| Tennessee Titans | Dominique Edison | Activated from the Practice Squad |
| Tennessee Titans | Fernando Velasco | cut |
| Washington Redskins | Sam Paulescu | cut |
| Washington Redskins | Lendy Holmes | Activated from the Practice Squad |
| Friday, November 13, 2009 |
| Team | Player | Transaction |
| Cincinnati Bengals | Roy Williams | Placed on IR, forearm |
| Cincinnati Bengals | Maurice Purify | Activated from the Practice Squad |
| Cleveland Browns | Alex Field | practice squad addition |
| Cleveland Browns | Keith Grennan | practice squad deletion |
| Miami Dolphins | J.D. Folsom | cut |