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Santiago has been suspended for 80 games after testing positive for exogenous testosterone, in violation of MLB's Joint Drug Prevention and Treatment program, Mark Feinsand of MLB.com reports.

Santiago faced a 10-game ban earlier in the season for having a foreign substance on his glove. He'll now face a lengthier suspension and will not appeal. Santiago should be able to serve about 55 games of the suspension by the end of the campaign, meaning he could be reinstated at some point in May of the 2022 season.

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