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Philadelphia will try to extend its two-game winning streak when it hosts Portland on Monday night. The 76ers are coming off consecutive home victories over Detroit and Atlanta. Portland had its two-game winning streak halted in a 125-113 loss at Charlotte on Sunday.

Tip-off is 7 p.m. ET at the Wells Fargo Center. Philadelphia is favored by six points in the latest 76ers vs. Trail Blazers odds from Caesars Sportsbook, and the over-under is set at 220.5. Before entering any Blazers vs. Sixers picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned almost $9,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model finished up almost $600 on its top-rated picks last season and enters Week 2 of the 2021-22 NBA season on a stunning 103-68 roll on top-rated NBA picks against the spread. Anyone following it has seen huge returns.

Now, the model has set its sights on 76ers vs. Trail Blazers. You can head to SportsLine to see its picks. Here are several NBA betting lines for Blazers vs. Sixers:

  • 76ers vs. Trail Blazers spread: 76ers -6
  • 76ers vs. Trail Blazers over-under: 220 points

What you need to know about the 76ers

Philadelphia split its first four games of the season, but it has now won its last two contests. The Sixers dominated Atlanta on Saturday, notching a 122-94 blowout in a game that featured two of the top teams in the Eastern Conference. Tobias Harris led Philadelphia in scoring for the third time this season, posting 22 points and 11 rebounds.

Point guard Ben Simmons remains sidelined for personal reasons, but Philadelphia is receiving plenty of help from its bench. Third-year guard Matisse Thybulle had 11 points, four steals and three blocks in the win over Atlanta. The 76ers are in an excellent scheduling spot on Monday, playing their third consecutive home game following a day off.

What you need to know about the Blazers

Portland's defensive numbers have not been great this season, but the Trail Blazers rank fifth in the NBA offensively. They are scoring 113.8 points per game, led by shooting guard CJ McCollum's average of 24.3. Star point guard Damian Lillard is off to a slow start by his standards, scoring 18.3 points per game.

Lillard will be motivated to bounce back from a poor performance on Sunday, where he shot just 5 of 20 overall. The Trail Blazers have always bounced back under Lillard's leadership, so there is no reason to expect things to change on Monday. They have covered the spread in six of their last seven games against Philadelphia. 

How to make 76ers vs. Trail Blazers picks

The model is leaning over on the total, and it's also generated a point-spread pick that is hitting in almost 70 percent of simulations. You can only see the pick at SportsLine.

So who wins Blazers vs. 76ers? And which side of the spread hits almost 70 percent of the time? Visit SportsLine to find out, all from the model that has crushed its NBA picks