The Pittsburgh Pirates aim to keep a positive start going on Tuesday. Pittsburgh is 8-8 overall after winning three of the last four games, and the Pirates are 4-2 at PNC Park this season. On Tuesday, the Pirates will host the Milwaukee Brewers, with Milwaukee looking to repeat a three-game sweep against Pittsburgh earlier in April. The Brewers are 10-7 overall and 5-4 on the road to begin the season.

Caesars Sportsbook lists the Brewers as -170 money-line favorites (risk $170 to win $100) for this 6:35 p.m. ET first pitch. The total number of runs Vegas thinks will be scored, or the over-under, is seven in the latest Brewers vs. Pirates odds. Before making any Pirates vs. Brewers picks, you need to see the MLB predictions and betting advice from SportsLine's advanced computer simulation model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a sizzling start to the 2022 season. It's on a 25-11 roll on top-rated MLB money-line picks through three weeks, returning almost $1,100 for $100 players. Anyone following it has seen huge returns.

Now, the model has set its sights on Brewers vs. Pirates, and just revealed its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Now, here are several MLB odds and betting lines for Pirates vs. Brewers:

  • Brewers vs. Pirates money line: Brewers -170, Pirates +150
  • Brewers vs. Pirates over-under: 7 runs 
  • Brewers vs. Pirates run line: Brewers -1.5 (-105)
  • MIL: The Brewers are 5-4 in road games 
  • PIT: The Pirates are 4-2 in home games
Featured Game | Pittsburgh Pirates vs. Milwaukee Brewers

Why you should back the Brewers

Milwaukee's pitching staff is very impressive, and the Brewers are sending an elite starting pitcher to the bump on Tuesday. Two-time All-Star Brandon Woodruff takes the ball for Milwaukee, and the 29-year-old right-hander posted a 2.56 ERA in 30 starts during the 2021 season. Woodruff struck out 10.6 batters per nine innings and walked only 2.2 batters per nine innings last season, and he finished in the top five in NL Cy Young voting. 

Woodruff has been impressive for a long time, posting a 3.11 ERA in 431.2 innings across five seasons, and right-handers particularly struggle against him. Woodruff has allowed a .587 OPS to right-handed batters in his career, and Woodruff also has a career 3.41 ERA on the road. When he leaves the game, the Brewers can also rely on a very good bullpen. Milwaukee ranks in the top three of the NL in wins above replacement among relief groups, and the relievers have a 3.39 ERA and 10.03 strikeouts per nine innings in 2022. 

Why you should back the Pirates

The Pirates should benefit from Milwaukee's lack of offensive punch. The Brewers rank near the bottom of the National League in myriad offensive categories this season, including a .201 batting average, .275 on-base percentage, and .325 slugging percentage. Milwaukee has only 56 runs scored in 17 games, and the Brewers have only 12 home runs. The Brewers are also below-average in walk rate (8.5 percent) and strikeout rate (25.0 percent), and Pittsburgh's bullpen is solid. 

The Pirates boast a 3.75 ERA in 74.1 innings of relief work, and the team's relievers average 2.46 strikeouts for every walk in 2022. Though starter Mitch Keller's season-long numbers aren't great (0-3, 6.23 ERA), he did hold the Brewers to just one earned run in 5.1 innings in his last start. On the position player side, Pittsburgh is keyed by Ke'Bryan Hayes, with the 25-year-old third baseman bringing a multi-faceted skill set. Hayes is a tremendous defensive player, and he has five doubles to go along with a .327/.407/.423 slash line in 2022.

How to make Brewers vs. Pirates picks

SportsLine's model is leaning over on the total, projecting 9.2 combined runs, and it says one side of the money line has all the value. You can only get the model's MLB picks at SportsLine.

So who wins Brewers vs. Pirates? And which side has all the value? Visit SportsLine now to find out which side of Brewers vs. Pirates you need to jump on Tuesday, all from the model that has crushed its MLB picks, and find out.