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Wednesday's soccer slate in Europe is a big one, but in Saudi Arabia arguably the biggest game in the world will be played as Real Madrid face Barcelona in El Clasico. The meeting outside of Spain is in the semifinals of the Spanish Super Cup, with the winner taking on either Atletico Madrid or Athletic Bilbao on Sunday. Barca have had their hands full during an up-and-down season as they look to find their footing under new boss Xavi. Real Madrid are the top team in Spain with an electric attack and the clear favorite to win this game, this competition and La Liga.

Here are the three players who need to step up for Barca to pull off the upset on Wednesday.

1. Gerard Pique 

Gerard Pique has gone the full 90 minutes in 12 of his team's last 14 games, and you can bet his friend Xavi will count on him here. While Pique is nowhere near the player he once was, he is still a reference point in the side and somebody who can make an impact on both ends.

And what this is about is basically limiting damage as Real are almost certain to score. Barca have conceded a goal in eight of their last 10 games, while Real had a streak of 10 consecutive games scoring before surprisingly failing to scoring in two of their last five. But when you mix an elite attack like Real's with an inconsistent defense in Barca, it could be a rough night. Pique will need to keep his positioning, be quick to react on Karim Benzema and limit those mistakes that have contributed to his regression. If he can be on his game and not fall victim to the technical mastery of Real's attack, then the underdogs will have a chance.

2. Sergio Busquets

Sergio Busquets is arguably the most important piece for Barca in this game, trying to combating a possession-heavy Real. While he doesn't offer much defensively, his ability to retain the ball and distribute it will be crucial to trying to win the battle of possession. Real Madrid typically win the majority of possession, often achieving over 60 percent. They've only lost it twice in the last 14 games. One of those was El Clasico on Oct. 24, with Real Madrid beating Barca 2-1. Los Blancos had 48 percent of the ball, and it directly correlates to the shots they had. In the two games Real have lost the fight for possession since early October, they produced 11.5 shots per game (against Real Sociedad and Barca). In all the other matches, they've averaged 15 shots per game and as high as 36. 

Busquets is going to need to be on the ball often, quick to get rid of it and avoid pressure, and he also needs to do a good job pushing an attacker one way to create double teams. If he goes in stabbing for the ball, his lack of pace could see Real get free multiple times. A throwback performance from Busquets in the middle is a must.

3. Ousmane Dembele

This Real defense has been super strong with Eder Militao and David Alaba, but they are prone to committing silly fouls. Be it the penalty conceded against Valencia last weekend to the horrendous showing at home to Sheriff in the Champions League early in the season, they have to be cleaner. Because if they aren't, this is the type of game where somebody like Ousmane Dembele can turn the tide. Yeah, I know, I know -- he's been average signing joining from Borussia Dortmund in 2017. But his elite pace and technical ability, when going down the flanks, can cause some damage and provide Barca opportunities to score from dead-ball situations.