Getty Images

Two teams at opposite ends of the English Premier League table collide when Manchester United host Leeds United on Wednesday at Old Trafford. The Red Devils are pushing for a top-four spot and sit in third place in the EPL table with 42 points. They are coming off a 2-1 win over Crystal Palace on Saturday. Meanwhile, the Whites have endured a week of upheaval with the team sacking American manager Jesse Marsch on Monday. Leeds United are in danger of falling into the relegation zone, sitting in 17th in the Premier League table with 18 points. 

Kickoff is at 3 p.m. ET. Caesars Sportsbook lists Manchester United as the -215 favorites (risk $215 to win $100) in the latest Manchester United vs. Leeds United odds, with Leeds the +550 underdogs. A draw is priced at +340 and the over/under for total goals scored is 2.5. Before locking in any Leeds United vs. Manchester United picks, make sure you check out the English Premier League predictions and best bets from SportsLine soccer insider Martin W. Green.

After working in the sports betting industry for several years, Green became a professional sports writer and handicapper and has covered the game worldwide. Since then, his European soccer picks have been spot-on. Green has generated almost $33,000 for $100 bettors since the 2017-18 season, and he has his finger on the pulse of the game all over the globe.

Now, Green has broken down the Leeds United vs. Man Utd matchup from all sides and just locked in his picks and Premier League predictions. You can head to SportsLine now to see his picks. Here are the betting lines and trends for Man Utd vs. Leeds:

  • Manchester United vs. Leeds spread: Man U -1.5 (+125), Leeds +1.5 (-160)
  • Manchester United vs. Leeds over/under: 2.5 goals
  • Manchester United vs. Leeds money line: Man U -215, Leeds +550, Draw +340
  • MAN: David de Gea is tied for third in the league in clean sheets (three)
  • LEE: Leeds rank 10th in the EPL in xG (expected goals) this season (1.55)
  • Manchester United vs. Leeds picks: See picks here

Why you should back Manchester United

The Red Devils have dominated the series against Leeds. In 28 previous Premier League matchups between the sides, Man United have 16 wins and eight draws. At Old Trafford alone, the Red Devils have 10 wins and four draws against the Whites.

In addition, Man United face a Leeds side that has struggled scoring recently. The Whites are scoreless in their last two matches – a 1-0 loss to Nottingham Forest on Sunday and a 0-0 draw to Brentford on Jan. 22. In six matches since play resumed after the World Cup, Leeds have scored just four goals.

Why you should back Leeds United

The Whites will be facing a Manchester United side that will be without six first team players on Wednesday. Among those out will be top playmaker Christian Eriksen, who is out until at least the end of April with an ankle he injured on Jan. 28. At the time of his injury he was tied for second in the EPL in assists with seven. Also, Casemiro, who is serving the first game of a three-game suspension, will not be available on Wednesday.

In addition, advanced stats suggest that Leeds have been unlucky offensively this season. The Whites rank 10th in the EPL in xG (expected goals) per game this season (1.55) yet they're averaging just 1.30 goals. The -0.25 difference between expected goals and actual goals is the ninth worst in the league.

How to make Leeds United vs. Manchester United picks

Green has analyzed this Premier League match from every possible angle. He is leaning Over on the goal total and has locked in three total best bets, including one that pays plus-money. Head to SportsLine to see his analysis and top picks.

So who wins Manchester United vs. Leeds on Wednesday? And where does all the betting value lie? Visit SportsLine now to find out which wagers in Leeds vs. Manchester United have all the value, all from the soccer expert who has generated almost $33,000 for $100 bettors since the 2017-18 season, and find out.