The Ohio State Buckeyes and the Rutgers Scarlet Knights are set to square off in a Big Ten battle at 3:30 p.m. ET on Saturday at SHI Stadium. Both teams are 3-1 on the season entering this Week 5 matchup, but Ohio State is 1-0 in conference play while Rutgers is 0-1. Ohio State has won all seven meetings since Rutgers joined the Big Ten in 2014 and has covered in five of those seven head-to-head matchups.

Rutgers is perfect against the spread so far this season, while Ohio State is an underwhelming 1-2-1. The Buckeyes are favored by 14 points in the latest Ohio State vs. Rutgers odds from Caesars Sportsbook. The over-under for total points is set at 57.5. Before entering any Rutgers vs. Ohio State picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,300 for $100 players on its top-rated college football picks against the spread. After going a sizzling 9-3 in Week 4, it also enters Week 5 of the 2021 season on an 81-61 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Ohio State vs. Rutgers. You can head to SportsLine to see its picks. Here are several college football odds for Ohio State vs. Rutgers:

  • Ohio State vs. Rutgers spread: Ohio State -14
  • Ohio State vs. Rutgers over-under: 57.5 points

What you need to know about Ohio State

The Buckeyes are coming off a dominant 59-7 win over an outmatched Akron last Saturday. Ohio State racked up 622 yards of total offense in the victory with Kyle McCord throwing for 319 yards and two touchdowns on just 18 pass attempts as the Buckeyes averaged a staggering 10.2 yards per play.

Garrett Wilson had four catches for 124 yards while TreVeyon Henderson rushed eight times for 93 yards and two scores. Meanwhile, the Buckeyes defense got to Akron's quarterbacks a total of nine times. Haskell Garrett had three sacks, while Tyleik Williams had a pair of sacks.

What you need to know about Rutgers

Rutgers is coming off a hard-fought 20-13 loss to Michigan last week. Greg Schiano's defense limited Michigan to 112 yards on the ground after Michigan had rushed for 335 yards or more against each of its first three opponents. Rutgers is allowing just 13.5 points per game and ranks seventh nationally in scoring defense.

On the other side of the ball, the Scarlet Knights haven't been prolific but they've done a good job of taking care of the football. Quarterback Noah Vedral has completed 67.9 percent of his passes for 762 yards and five touchdowns without an interception and Rutgers has only turned the ball over once in four games.

How to make Ohio State vs. Rutgers picks

The model has simulated Rutgers vs. Ohio State 10,000 times and the results are in. It is leaning under on the total and it's also generated a point-spread pick that is hitting in 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Ohio State vs. Rutgers? And which side of the spread is a must-back? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.