Mississippi State will take on Southern Miss at 3:30 p.m. ET on Saturday at Davis Wade Stadium in Starkville. Southern Miss and Mississippi State gave bettors opposite luck in their past games. The Golden Eagles delivered fans and bettors alike a win by covering the 24.5-point spread against Alcorn State. No such luck for the bettors backing the Bulldogs. Despite pleasing their fans with a victory, the team failed to cover their 19-point spread against Louisiana Lafayette. The Bulldogs are favored by 16.5 points over the visiting Golden Eagles in the latest Southern Miss vs. Mississippi State odds, while the Over-Under is set at 51. Before you make any Southern Miss vs. Mississippi State picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every FBS college football game 10,000 times, and those who have followed it have seen massive returns. Over the past four years, this proprietary computer model has generated a jaw-dropping $4,530 profit for $100 bettors on its top-rated spread picks. The model enters Week 2 of the 2019 college football season on a blistering 52-31 run on all top-rated picks. It also called Auburn (-3.5) covering against Oregon and Alabama (-34) covering a nearly five-touchdown spread against Duke in Week 1. Anybody who has been following it is way up.

Now, it has simulated Mississippi State vs. Southern Miss 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You can only see the pick at SportsLine.

The Bulldogs were successful in their last outing against Louisiana, and they didn't afford Louisiana any payback this time around. Mississippi State was able to grind out a solid victory over Louisiana last week, winning 38-28. Running back Kylin Hill propelled the Bulldogs' offense to their first victory of the season, rushing for 197 yards and a touchdown on 27 carries. Transfer quarterback Tommy Stevens also had a strong showing in his Mississippi State debut, completing 20 passes for 236 yards and two touchdowns. 

Meanwhile, when you finish with 206 more yards than your opponent like the Golden Eagles did last Saturday, a favorable outcome is almost sure to follow. Everything went their way against Alcorn State as they made off with a 38-10 win. Quarterback Jack Abraham was extremely impressive for the Golden Eagles, passing for almost 300 yards and a score. Wide receiver Jordan Mitchell also shined in Southern Miss' victory, catching seven passes for 133 yards. Defensively, the Golden Eagles will lean on their front seven against the Bulldogs, which ranked third in the nation in yards allowed per game last year, closing the season allowing only 278.8 on average. 

So who wins Mississippi State vs. Southern Miss? And which side of the spread is hitting in almost 60 percent of simulations? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.