Leon Edwards hasn't set foot in the Octagon in 600 days, while Belal Muhammad has taken just 28 days off from fighting ahead of their clash in the main event of UFC Fight Night: Edwards vs. Muhammad on Saturday. The ranked welterweights will close the curtain on the main UFC fight card from fabulous Las Vegas. The main UFC card is set for 8 p.m. ET. Their contrast in activity levels is just one of many differences between the third-ranked Edwards and No. 13-ranked Muhammad.

The surging Muhammad told the media this week that he believes his consistency will be a major advantage, in part because he is more mentally prepared for live combat than Edwards, who didn't fight at all in 2020 largely due to pandemic-related travel restrictions. Edwards is a -250 favorite (risk $250 to win $100), while Muhammad is a +210 underdog in the latest Edwards vs. Muhammad odds from William Hill Sportsbook. In the co-main event, Misha Cirkunov (-135) faces Ryan Spann (+115) in a matchup of light heavyweight prospects. Before making any UFC Fight Night: Edwards vs. Muhammad picks of your own, make sure you check out the latest MMA predictions from SportsLine analyst Kyle Marley.

Marley won the first-ever "ToutMaster" UFC betting contest sponsored by MMAOddsBreaker and appears regularly on multiple MMA betting and daily Fantasy shows. He watches every single fight for every professional MMA card and does extensive research before each event.

Over the past 25 months, $100 bettors who have followed Marley's picks are up more than $21,000. Already in 2021, the accomplished MMA analyst has built on his memorable 2020 run and has now connected on 28 of his last UFC 40 main-event picks, a stretch that includes a streak of five straight underdogs.

Just last week at UFC Fight Night, Marley told SportsLine members to back Aleksandar Rakic (-160) against former title-contender Thiago Santos (+140) in a light heavyweight matchup on the main card. Rakic controlled the action on his way to a unanimous-decision victory to give Marley's followers another easy winner. Anyone who has consistently followed Marley is way up.

Now, with UFC Fight Night: Edwards vs. Muhammad Marley has carefully studied every matchup on the card, identified the best value in the UFC odds and released his MMA picks for every fight. Those selections are only available here.

Leon Edwards vs. Belal Muhammad preview

Edwards (18-3) is the highest-ranked welterweight who has yet to fight for the title. Kamaru Usman already has defeated top-ranked contender Colby Covington, Gilbert Burns, and fourth-rated Jorge Masvidal, so Edwards would be a logical next choice should he win impressively. Coincidentally, his last UFC defeat came against Usman by decision in December 2015.

Various pandemic-related obstacles caused multiple proposed fights for Edwards to be canceled, but he found an eager opponent in Muhammad (18-3), who has adamantly pleaded for a highly-ranked opponent following his last two victories.

The Chicago native has flustered opponents with his furious pace and wrestling-based attack that hinders their ability to craft an assault of their own. He is coming off a unanimous decision against Dhiego Lima and happily took the call from UFC President Dana White to step in for Khamzat Chimaev, the ultra-hyped prospect who is unable to fight because of lingering effects from a battle with COVID-19. You can see Marley's coveted Edwards vs. Muhammad picks here.

UFC Fight Night: Edwards vs. Muhammad predictions

We'll share one of Marley's UFC Fight Night picks here: He is siding with Gavin Tucker (+100) to outlast Dan Ige (-120) by decision in a battle of featherweight contenders.

The No. 8-ranked Ige (14-3) saw a six-fight winning streak come to a halt in his last performance, but it hardly dimmed his status as a promising contender. This is because he went five full rounds before losing a decision to Calvin Kattar, the No. 6-ranked contender whom many believe will be a future title-challenger. The 29-year-old Hawaiian also notched decision victories over veterans Mirsad Bektic and Edson Barboza in 2020.

Tucker (13-1) is currently unranked, but that could change should he pull off his fourth consecutive UFC victory on Saturday. The 34-year-old Canadian split his first two UFC bouts before reeling off a win streak that saw him step up in level of competition in his last performance. Tucker earned a unanimous decision against fellow rising contender Billy Quarantillo in December.

"I will roll with Tucker as the underdog pick on the scorecards for being the sharper striker and landing the harder shots," Marley told SportsLine.

How to make UFC Fight Night picks

Marley also has strong picks for Edwards vs. Muhammad and every other bout on the UFC Fight Night card. He's also backing one fighter "who is the better striker, wrestler, and grappler." Those UFC picks are only available at SportsLine.

Who wins Edwards vs. Muhammad? And how exactly does each fight end? Visit SportsLine now to get detailed picks on every fight at UFC Fight Night, all from the incomparable expert who's up more than $21,000 on MMA in the past 25 months, and find out.

UFC Fight Night: Edwards vs. Muhammad odds

Leon Edwards (-250) vs. Belal Muhammad (+210)
Misha Cirkunov (-135) vs. Ryan Spann (+115)
Dan Ige (-120) vs. Gavin Tucker (+100)
Angela Hill (-380) vs. Ashley Yoder (+310)
Manel Kape (-130) vs. Matheus Nicolau Pereira (+110)
Darren Stewart (-175) vs. Eryk Anders (+155)
JJ Aldrich (-145) vs. Cortney Casey (+125)
Rani Yahya (-300) vs. Ray Rodriguez (+250)
Charles Jourdain (-250) vs. Marcelo Rojo (+210)
Jonathan Martinez (-280) vs. Davey Grant (+240)
Gloria de Paula (-160) vs. Jinh Yu Frey (+140)
Matthew Semelsberger (-130) vs. Jason Witt (+110)