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The UCLA Bruins and the Arizona Wildcats will face off in a Pac-12 clash at 10:30 p.m. ET on Saturday, October 9 at Arizona Stadium. Arizona is 0-4 overall and 0-2 at home, while the Bruins are 3-2 overall and 1-0 on the road. Arizona is 2-2 against the spread and UCLA is 3-2 ATS in 2021.

The Bruins are favored by 16 points in the latest Arizona vs. UCLA odds from Caesars Sportsbook, and the over-under is set at 61. Before locking in any UCLA vs. Arizona picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It also enters Week 6 of the 2021 season on a 12-4 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Arizona vs. UCLA and just released its picks and predictions. You can head to SportsLine now to see the model's CFB picks. Here are several college football odds and betting lines for Arizona vs. UCLA:

  • Arizona vs. UCLA spread: Arizona +16
  • Arizona vs. UCLA over-under: 61 points
  • Arizona vs. UCLA moneyline: UCLA -800, Arizona +550

What you need to know about Arizona

Arizona is winless in 2021, and aside from their 21-19 loss to FCS opponent Northern Arizona, the Wildcats haven't even really been competitive. Arizona is scoring just 17 points per game (and giving up 31 per game), so something will have to have drastically changed from their last outing for them to keep pace UCLA on Saturday.

Jordan McCloud is set to get the start at quarterback for the Wildcats, and he could find some success against UCLA's pass defense, which is allowing 321.4 yards per game.

What you need to know about UCLA

UCLA suffered a bitter loss on Saturday, failing to capitalize on an early lead against the Arizona State Sun Devils in a key Pac-12 South matchup. Quarterback Dorian Thompson-Robinson, continued his run of strong play in 2021, throwing for 235 yards and a touchdown in addition to picking up 93 yards on the ground.

UCLA has flashed signs of greatness at times in 2021, but still has two disappointing losses (to Fresno State and ASU) on its resume. The Bruins are clearly the better team this week, so look for them to right their ship and take out some of their frustrations on Arizona on Saturday night.

How to make Arizona vs. UCLA picks

The model has simulated Arizona vs. UCLA 10,000 times and the results are in. We can tell you that the model is leaning over on the point total, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You can only see the model's UCLA vs. Arizona pick at SportsLine.

So who wins UCLA vs. Arizona? And which side of the spread has all the value? Visit SportsLine now to see which side of the UCLA vs. Arizona spread to jump on, all from the advanced model that is on an 12-4 run on top-rated picks, and find out.