The UTSA Roadrunners (2-2) travel to Floyd Stadium to play the Middle Tennessee Blue Raiders (3-1) in a Conference USA matchup on Friday night. The Roadrunners torched Texas Southern 52-24 in Week 4. On the other side, MTSU stunned Miami (Fla.) 45-31 last week, going on the road and winning 45-31 despite entering the game as a big 25.5-point underdog.

Kickoff in Murfreesboro, Tenn., is set for 7:30 p.m. ET on CBS Sports Network. The Roadrunners are 4.5-point favorites in the latest UTSA vs. MTSU odds from Caesars Sportsbook. The over/under for total points is set at 64. Before finalizing any MTSU vs. UTSA picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on MTSU vs. UTSA and just locked in its picks and CFB predictions. You can visit SportsLine now to see the model's picks. Here are the college football odds and betting lines for UTSA vs. MTSU:

  • UTSA vs. MTSU spread: UTSA -4
  • UTSA vs. MTSU over/under: 64 points
  • UTSA vs. MMTSU money line: UTSA -195, MTSU +162
  • UTSA: Roadrunners are 5-1 ATS in their last six games on turf
  • MTUS: Blue Raiders are 5-1 ATS in their last six games overall
  • UTSA vs. MTSU picks: See picks at SportsLine
Featured Game | Middle Tenn. Blue Raiders vs. UTSA Roadrunners

Why UTSA can cover

The Roadrunners have dynamic weapons at receivers. They have showcased their ability to create space and consistently get open. Senior receiver Joshua Cephus is a big-body weapon (6-foot-3) who can line up inside or out. Cephus is amazing at the catch point and can easily high-point a jump ball. The Texas native is second on the team in catches (29) and receiving yards (412). He has gone over 100-plus yards in three of the four games played.

Senior receiver Zakhari Franklin is an all-around weapon for this unit. Franklin understands leverage and knows how to attack defenders. The Texas native owns outstanding hands and body control. He's first on the team in catches (32) along with 393 yards and four touchdowns. Franklin is a consistent threat, logging 80-plus yards in all four games thus far. Last week, he reeled in six catches for 87 yards with a score. 

Why MTSU can cover 

The MTSU offense has plenty of dynamic playmakers. The Blue Raiders have nice balance on this side of the ball. Sophomore running back Frank Peasant is a patient ball-carrier who gets the most of every carry. Peasant can put his foot in the ground and get upfield. The Florida native is leading the team with 63 carries for 292 yards with six touchdowns. On Sept. 17, he had 13 carries for 122 yards and three touchdowns.

Junior receiver DJ England-Chisolm is coming off a massive performance in which he showcased his blazing deep speed. In the win over Miami, Chisolm reeled in two receptions for 169 yards and two touchdowns. He baked an opposing cornerback for a 98-yard score in the contest. Senior receiver Izaiah Gathings owns the size (6-foot-4, 222 pounds) to be an effective threat in the passing game. Gathings uses his stature to win contested catches and outmuscle defenders. He's caught 24 passes for 175 yards through four games. 

How to make MTSU vs. UTSA picks

SportsLine's model is leaning Under on the total, projecting 57 combined points. It has also generated an against the spread pick that cashes in well over 50% of simulations. You can only get the model's pick at SportsLine

So who wins UTSA vs. MTSU? And which side of the spread cashes in well over 50% of simulations? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that finished the past six-plus years up more than $3,100 on its FBS college football picks, and find out.