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Liverpool will try to stay right in the middle of the league title race when it hosts Southampton on Saturday in an English Premier League match at Anfield. The Reds (7-4-1) sit in third place, four points behind leader Chelsea and one behind Manchester City. The Blues take on Manchester United on Sunday, while City faces a tough test against fourth-place West Ham the same day. Liverpool has won seven of its past eight meetings with Southampton (3-5-4) and has outscored it 12-0 in the last four matchups at Anfield. The Reds routed Arsenal 4-0 in their last league match last Saturday and beat FC Porto 2-0 on Wednesday in the Champions League, while the Saints lost 2-1 to 19th-place Norwich City last weekend.

Kickoff is set for 10 a.m. ET. Liverpool is the -345 favorite (risk $345 to win $100) on the 90-minute money line in the latest Liverpool vs. Southampton odds from Caesars Sportsbook. Southampton is the +950 underdog, a draw is priced at +460 and the over-under for total goals is set at 3.5. Before making any Southampton vs. Liverpool picks or any English Premier League predictions, you have to see what proven soccer insider Martin Green has to say

After working in the sports betting industry for several years, Green became a professional sports writer and handicapper and has covered the game worldwide. Since then, his European soccer picks have been stunningly accurate. Green has generated more than $36,000 for $100 bettors since the 2017-18 season, and he has his finger on the pulse of the game all over the globe.

Now, Green has broken down the Liverpool vs. Southampton matchup from every angle and just locked in his coveted Premier League picks and predictions. You can head to SportsLine to see Green's EPL picks. Here are the Premier League odds and betting lines for Southampton vs. Liverpool:

  • Liverpool vs. Southampton: Liverpool -1.5 (-135)
  • Liverpool vs. Southampton over-under: 3.5 goals 
  • Liverpool vs. Southampton money line: Liverpool -345, Southampton +950, Draw +460
  • LVP: Trent Alexander-Arnold has 38 assists in his last 113 league games 
  • SH: James Ward-Prowse created 41 chances on set pieces last season

Why you should back Liverpool

The Reds have outscored opponents 14-5 at Anfield this season and lead the Premier League with 35 goals. They also have the most shots (233) and shots on target (78) and hold the ball for 62.2 percent of their matches (second). Liverpool had already clinched the top spot in its Champions League group and won the match despite resting some key players. Mohamed Salah did start the game and scored one of the goals, and he leads the EPL with 11 this season and is tied for most assists with seven. He has 16 goals in 15 matches across all competitions.

Forward Sadio Mane and key defender Joel Matip also started Wednesday, but players like defensive stalwart Virgil Van Djik and set piece standout Trent Alexander-Arnold should be fresh. Van Djik plays a crucial role in the middle alongside Matip, with the Dutch star's combination of size and instincts a constant concern for opposing attackers. The Reds have allowed the third-fewest shots (116) and shots on target (37) in the Premier League. Mane has scored seven goals, and Alexander-Arnold has the third-most assists in the league with six.   

Why you should back Southampton

The Saints have played to draws with both Manchester City and Manchester United in league play this season. They also took Chelsea to the brink in the League Cup, losing on penalties after a 1-1 draw. Southampton has young talent in the attack, with Adam Armstrong and Che Adams each scoring twice. Adams has five goals in his last six matches in all competitions, including two with Scotland in World Cup Qualifying. Armstrong is off to a slow start after scoring 28 goals with Blackburn last season, but he has a goal and two assists in his past three games.

James Ward-Prowse is one of the most dangerous players in the Premier League on set pieces. He has scored twice, with both goals coming on penalty kicks. Southampton has five clean sheets in the 12 matches and has conceded just 14 goals, tied for fifth-fewest in the league. The Saints hound opposing attackers, and they rank sixth in tackles won (140), with central defender Mohammed Salisu fourth in the EPL with 37. They control the ball more than 51 percent of the time (eighth in EPL) and have allowed the fifth-fewest shots in the league (137). 

How to make EPL and Liverpool vs. Southampton picks

Green has analyzed the Liverpool vs. Southampton match from all sides, and he is leaning over on the goal total. He also provides his two confident best bets, including an exact score play that would pay off huge, and has a full breakdown of the match. He's only sharing his Premier League picks here.

So who wins Southampton vs. Liverpool in Saturday's English Premier League matchup? And where does all the betting value lie? Visit SportsLine now to see the best bets for the Liverpool vs. Southampton match, all from the European soccer expert who has generated well over $36,000 for $100 bettors over the past four seasons, and find out.