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A Sun Belt matchup features the Southern Miss Golden Eagles (1-5) and the South Alabama Jaguars (3-3) squaring off in one of the first games of the Week 8 college football schedule. South Alabama is currently second in the conference in total defense (339.7), while Southern Miss is eighth (395.3). 

Kickoff from Hancock Whitney Stadium in Mobile is set for 7:30 p.m. ET. The Jaguars are 18.5-point favorites in the SportsLine consensus Southern Miss vs. South Alabama odds, while the over/under for total points is 51.5. Before making any South Alabama vs. Southern Miss picks, you need to see the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a stunning profit of more than $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed the model has seen huge returns.

Now, the model has set its sights on Southern Miss vs. South Alabama and identified its picks and predictions. You can visit SportsLine now to see the model's CFB picks. Here are several college football odds and trends for South Alabama vs. Southern Miss:

  • Southern Miss vs. South Alabama spread: Jaguars -18.5
  • Southern Miss vs. South Alabama over/under: 51.5 points
  • Southern Miss vs. South Alabama money line: Jaguars -1034, Golden Eagles +653
  • USM: Has hit the team total under in two of last three away games 
  • USA: Has hit the game total over in eight of 13 games 
  • Southern Miss vs. South Alabama picks: See picks at SportsLine
  • Southern Miss vs. South Alabama live stream: fubo (try for free)

Why South Alabama can cover

South Alabama enters this matchup as one of the top defenses in the conference. The Jaguars rank second in total defense (339.7), fourth in run defense (116.2) and third in scoring (22.2). They allowed 20 or fewer points in three matchups thus far. Senior defensive lineman Jamie Sheriff is a relentless defender who plays and gives maximum effort. He logged 22 total tackles, four tackles for loss, five QB hits and two sacks.

Senior linebacker Trey Kiser has a nose for the ball. The Oklahoma native leads the team in total tackles (39) and tackles for loss (6). He's recorded at least six tackles in three straight games. Junior safety Jaden Voisin makes solid plays on the ball when in coverage. Voisin has notched 34 total tackles, two pass breakups and two interceptions. See which team to back here.

Why Southern Miss can cover

Southern Miss is currently third in the conference in passing yards allowed (207.2). The Golden Eagles have an effective defensive line that gets after the quarterback. They are ranked sixth in the conference in team sacks (17) for a loss of 105 yards. USM has five players with at least 1.5 sacks on the season. 

Linebacker Jalil Clemons utilizes his quick first step and violent hands to get past blockers. He leads the team in sacks (3) and has recorded one in three straight games. Senior safety Jay Stanley is an athletic and instinctive difference-maker. The Mississippi native has secured 33 total tackles while leading the team in interceptions (2) and forced fumbles (2). In Week 6 versus Texas State, Stanley had four total tackles, one forced fumble and one fumble recovery. See which team to pick here.

How to make Southern Miss vs. South Alabama picks

SportsLine's model is leaning Over the point total, predicting 53 combined points. The model also says one side of the spread hits well over 50% of the time. You can see the model's picks at SportsLine

So who wins South Alabama vs. Southern Miss, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has notched a profit of more than $2,000 on its top-rated college football spread picks, and find out.