It's been a challenging regular season for both Washington (4-7) and Washington State (6-5), but the in-state rivals can wrap it up on a high note with a win on Friday in the 2021 Apple Cup. Both sides are playing under an interim head coach. The Cougars enter this matchup bowl eligible after they knocked off Arizona last week. Washington has dropped three straight.  

Kickoff is set for 8 p.m. ET. in Seattle. The Cougars are one-point favorites in the latest Washington State vs. Washington odds from Caesars Sportsbook. The over-under for total points is set at 44.5. Before making any Washington vs. Washington State picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 13 of the 2021 season on a 39-25 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has locked in on Washington vs. Washington State and just revealed its picks and CFB predictions. You can head to SportsLine now to see the model's picks. Here are the CFB odds and betting lines for Washington State vs. Washington:  

  • Washington vs. Washington State spread: WSU -1
  • Washington vs. Washington State over-under: 44.5 points
  • Washington vs. Washington State money line: WSU -120, Washington +100
Featured Game | Washington Huskies vs. Washington State Cougars

Why Washington can cover

It hasn't been the season the Huskies envisioned and head coach Jimmy Lake was fired two weeks ago. But the Huskies have some notable strengths, including one of the best defenses in the Pac-12. They are tied for first in the conference in scoring defense, giving up just 21.1 points per game. They are particularly stingy against the pass, giving up just 133.6 yards per game through the air. 

Moving the ball on offense has been the challenge, but quarterback Dylan Morris has thrown for almost 2,500 yards and 14 touchdowns. He'll need to cut down on the mistakes, however, after also throwing for 12 interceptions. Sean McGrew (431 yards) is the leading rusher, while Jalen McMillan and Terrell Bynum have both surpassed 400 yards receiving. 

Why Washington State can cover

The Cougars bring one of the best passing attacks in the conference into this matchup. They average 260.4 yards through the air per game, good for second in the Pac-12. Quarterback Jayden de Laura leads the attack.

He's thrown for over 2,500 yards with 23 touchdowns and just nine interceptions. Calvin Jackson Jr. (887 yards) and Travell Harris (778) have been two of the Pac-12's most productive receivers. The Cougars are 7-3 against the spread this season and 3-1 ATS on the road. 

How to make Washington State vs. Washington picks

The model is going under on the total, projecting 43 combined points. It also says one side of the spread hits more than 50 percent of the time. You can only see the model's pick at SportsLine

So who wins Washington State vs. Washington? And which side of the spread hits more than 50 percent of the time? Visit SportsLine right now to see which side of the spread to back, all from the advanced model on a 39-25 run on its top-rated college football side picks, and find out.