Getty Images

Two European heavyweights collide in a Champions League quarterfinal when Paris Saint-Germain and Barcelona square off in the first leg on Wednesday at Parc des Princes in Paris. PSG are the reigning Ligue 1 champions and have won the league a record 11 times. This season, they are on pace to win their 12th title, holding a 10-point lead in the table with only six rounds remaining. Meanwhile, Barcelona are the reigning La Liga champions and have won the league 27 times, second only to Real Madrid. PSG and Barcelona will play the second leg of the quarterfinal on April 16 in Barcelona.

Kickoff is scheduled for 3 p.m. ET. PSG are the -105 favorites (risk $105 to win $100) in the latest PSG vs. Barcelona odds, with Barca the +270 underdogs. A draw is priced at +270 and the over/under for total goals scored is 2.5. Before you lock in your Barcelona vs. PSG picks or Champions League predictions, you must see what proven SportsLine soccer expert Jon "Buckets" Eimer has to say.

Eimer is a high-volume bettor who has vast knowledge of leagues and players across the globe. Since joining SportsLine, he has covered the English Premier League, Serie A, the FA Cup and much more. In 2023 he was red-hot, going 248-234-12 for a profit of $2,593 for $100 bettors.

Now, Eimer has broken down PSG vs. Barcelona from every angle and identified his picks and Champions League predictions. You can head to SportsLine now to see Eimer's picks. Here are the betting lines and trends for Barcelona vs. PSG:

  • PSG vs. Barcelona money line: PSG -105, Barcelona +270, Draw +270
  • PSG vs. Barcelona over/under: 2.5 goals
  • PSG vs. Barcelona spread: PSG -0.5 (-110), Barcelona +0.5 (-125)
  • PSG: Kylian Mbappe leads Ligue 1 in goals (24).
  • FCB: Robert Lewandowski is tied for seventh in La Liga in goals (13).
  • PSG vs. Barcelona: See picks at SportsLine

Why you should back PSG 

The last time these clubs played in the Champions League, Kylian Mbappe was unstoppable. In 2021, Mbappe scored a hat trick at Camp Nou and added another goal in Paris as PSG knocked out Lionel Messi and Barcelona, 5-2, on aggregate. This season, Mbappe leads Ligue 1 in goals (24) and ranks second in assists (six).

Mbappe and PSG will enter Wednesday's match well-rested. In Saturday's match against Clermont, PSG manager Luis Enrique rested goalkeeper Gianluigi Donnarumma and several other first-teamers. Mbappe did not play a full 90 minutes, coming on only midway through the second half. See which team to pick here.

Why you should back Barcelona

Barcelona's Robert Lewandowski remains a world-class goal scorer. The 35-year-old striker from Poland has scored 20 goals across all competitions for the Blaugrana and had a 21st taken away by VAR against Las Palmas. In the Round of 16 Champions League match against Napoli, Lewandowski scored in each of the two legs, leading Barca to a 4-2 victory on aggregate.

Lewandowski and the Blaugrana will face a PSG side that will be without its top two right backs. Nordi Mukiele will sit out the match while in concussion protocol. Achraf Hakimi will also miss the first leg due to a one-game suspension for an accumulation of yellow cards. See which team to pick here.

How to make Barcelona vs. PSG picks

Eimer has broken down Wednesday's Champions League match from every possible angle and is leaning Under 2.5 goals. He also has three best bets, including two that offer a plus-money payout, and a full breakdown of this match. He's sharing his Champions League match picks and analysis only at SportsLine.

So who wins Barcelona vs. PSG on Wednesday, and where does all the betting value lie? Visit SportsLine now to see which wagers in PSG vs. Barcelona have all the value, all from the soccer expert who was up more than $2,500 for $100 players in 2023, and find out.

How to get in-depth soccer coverage daily

The CBS Sports Golazo Network has you covered with soccer news, highlights, analysis, and exclusive games. The 24-hour digital network provides around-the-clock soccer viewing to fans across the country, including morning shows and live matches. It launched in April and has been a smashing success thus far, expanding its offerings every week. Watch the CBS Sports Golazo Network now here.

The CBS Sports Golazo Network provides soccer fans with wall-to-wall coverage of the most popular game in the world. Check it out now on CBSSports.com, the CBS Sports app for connected TV devices, the CBS Sports mobile app, Pluto TV or Paramount+.