The No. 13 Miami (FL) Hurricanes will try to bounce back from their 42-17 loss to top-ranked Clemson when they take on the Pittsburgh Panthers at noon ET on Saturday. Pitt quarterback Kenny Pickett (ankle) is questionable. Pittsburgh won three straight games to open the season and ranked as high as No. 21. The Panthers have since dropped consecutive one-point games to NC State and Boston College. Miami won and covered in its first three games before the setback against Clemson.

William Hill list the Hurricanes as 13-point favorites in the Miami vs. Pittsburgh odds, up from opening at -10.5. The over-under for total points is set at 47.5, down from 52. Before making any Pittsburgh vs. Miami picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $4,200 for $100 players on its top-rated college football picks against the spread. It is a sizzling 23-6 on top-rated picks through six weeks of the 2020 college football season, returning almost $1,300 in profit already. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Miami vs. Pitt. You can head to SportsLine to see its picks. Here are several college football odds for Pitt vs. Miami:

  • Miami vs. Pittsburgh spread: Miami -13.5
  • Miami vs. Pittsburgh over-under: 47.5 points
  • Miami vs. Pittsburgh money line: Miami -500, Pittsburgh +400

What you need to know about Pittsburgh

There are obvious concerns about Pittsburgh due to Pickett's status. During the week, coach Pat Narduzzi told reporters that Pickett isn't 100 percent healthy, but also said that he likes where he is right now. Pickett has been one of the nation's best quarterbacks thus far in 2020 as he's piled up 1,389 yards through the air, eight touchdowns and just three interceptions. He's also rushed for five scores. 

Even if he's limited or can't play, Pitt has strengths to fall back on. The Panthers haven't played quite as well defensively the past couple weeks, but they're still giving up just 18.2 points per game on the season. And with three wins on the season to go along with two losses by a combined total of two points, the Panthers are a tough team to blow out, meaning Miami will have to play extremely well to get the cover. 

What you need to know about Miami

Meanwhile, Miami might not have won anyway, but with 115 yards lost due to penalties, the Hurricanes really shot themselves in the foot on Saturday. They ended up on the wrong side of a painful 42-17 loss at the Clemson Tigers' hands. Miami was down 35-10 at the end of the third quarter, which was just too much to recover from. The Hurricanes' only offensive touchdown came on a rush from QB D'Eriq King. The Hurricanes did return a kick for a touchdown though and that could be key after a kicking game mistake cost Pittsburgh last week.

Miami will enter Saturday's ACC battle full of confidence. That's because the Hurricanes are 8-2 in their last 10 meetings against the Panthers. In addition, Miami is 16-4 in its last 20 home games. 

How to make Miami vs. Pittsburgh picks

The model has simulated Miami vs. Pittsburgh 10,000 times and the results are in. The model is leaning under on the total, and it also says one side of the spread hits in well over 50 percent of the time. You can only see the pick at SportsLine.

So who wins Miami vs. Pittsburgh? And which side of the spread is hitting in well over 50 percent of simulations? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.