Jim Mora Jr. and the UConn Huskies face an immense challenge on Saturday afternoon. UConn enters the week with a 1-2 record, and the Huskies hit the road to face the No. 4 Michigan Wolverines in Ann Arbor. The Huskies are coming off a 48-14 loss to Syracuse and facing an impressive opponent. Michigan is 2-0 this season with a pair of blowout victories and an all-time series lead of 2-0 against UConn.

Kickoff is set for noon ET. The Wolverines are 47.5-point favorites in the latest Michigan vs. UConn odds. The over/under for total points is set at 58.5. Before making any UConn vs. Michigan picks, you need to see the college football predictions and betting advice from SportsLine's advanced computer simulation model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It enters Week 3 of the 2022 college football season on a 50-41 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on UConn vs. Michigan and just locked in its picks and CFB predictions. You can head to SportsLine now to see the model's picks. Now, here are several college football odds and betting lines for Michigan vs. UConn: 

  • Michigan vs. UConn spread: Michigan -47.5 
  • Michigan vs. UConn over/under: 58.5 points 
  • CONN: The Huskies are 8-7 against the spread in the last 15 games 
  • MICH: The Wolverines are 12-4 against the spread in the last 16 games 
  • Michigan vs. UConn picks: See picks here

Why UConn can cover

UConn has statistical strengths on both sides of the ball to this point in the season, and the Huskies have an experienced head coach in Jim Mora. On defense, UConn has seven sacks in 2022, and opponents are averaging only 3.9 yards per carry while completing only 65.5% of passes. Linebacker Jackson Mitchell leads the entire country with 39 tackles this season, and Mitchell also leads UConn in both tackles for loss and sacks. 

Michigan has scuffled on third down, converting only 31% of chances, and UConn's offense is potent on the ground. The Huskies are averaging more than 200 rushing yards per game and 5.1 yards per carry this season, helping to keep the offense on schedule. UConn is also yielding less than 1.5 sacks per game, and running back Nathan Carter is enjoying a potent season. Carter has 384 yards on 59 carries this season, averaging 6.5 yards per tote and 128 yards per game.

Why Michigan can cover

After a Big Ten title a year ago, Michigan is off to a tremendous start in 2022. Jim Harbaugh's club is 2-0 with wins by a combined 100 points, and Michigan is No. 2 in the country with 53.5 points per game on offense. The Wolverines are averaging 514 total yards per game, including 251 yards per game on the ground, and Michigan is generating 10.5 yards per pass attempt while completing 70% of throws. On defense, Michigan is also playing at a high level, yielding only 125 passing yards per game and 4.4 yards per pass attempt. 

Opponents have only one passing touchdown against Michigan, with the Wolverines allowing a completion rate of only 50.9% with eight sacks in two games. UConn has at least two turnovers in each game this season, and the Huskies are giving up more than 400 yards per game on defense. UConn also hasn't posted a winning season since 2010, with only one FBS win over the last three seasons and a 16-year drought since last defeating a Big Ten opponent.

How to make UConn vs. Michigan picks

SportsLine's model is leaning Over on the total, with each team's leading rusher projected for at least 5.0 yards per carry. The model also says one side of the spread hits more than 50% of the time. You can only see the model's pick at SportsLine

So who wins Michigan vs. UConn? And which side of the spread hits more than 50% of the time? Visit SportsLine now to see which side of the UConn vs. Michigan spread you need to jump on Saturday, all from the model that has crushed its college football picks, and find out.