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USATSI

The No. 13 Penn State Nittany Lions (6-1) host the No. 2 Ohio State Buckeyes in an important Big Ten showdown on Saturday afternoon. Both of these teams have explosive and exciting offenses. The Buckeyes are first in the conference in scoring (49.6) and total offense (517.4). Meanwhile, the Nittany Lions are fourth in scoring (33.4) and seventh in total offense (423.6). The Buckeyes are 4-2 against the spread when facing FBS competition this year while Penn State has a 4-3 ATS mark. 

Kickoff from Beaver Stadium in University Park is set for noon ET. Caesars Sportsbook lists the Buckeyes as 15.5-point favorites in the latest Ohio State vs. Penn State odds. The over/under for total points is set at 60.5. Before locking in any Penn State vs. Ohio State picks, you need to see the college football predictions and betting advice from SportsLine's advanced computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Ohio State vs. Penn State and locked in its picks and CFB predictions. You can head to SportsLine now to see the model's picks. Here are several college football odds and betting lines for Penn State vs. Ohio State:

  • Ohio State vs. Penn State spread: Buckeyes -15.5
  • Ohio State vs. Penn State over/under: 60.5 points
  • Ohio State vs. Penn State money line: Buckeyes -600, Nittany Lions +430
  • OSU: Buckeyes are 10-1-1 ATS in their last 12 games in October
  • PSU: Underdog is 5-1 ATS in their last six meetings
  • Ohio State vs. Penn State picks: See picks at SportsLine

Why Ohio State can cover

The Buckeyes love to run the ball and dominate the time of possession. They rank third in the Big Ten in rushing yards per game (204.9). Sophomore running back TreVeyon Henderson has been carrying the ground attack over the past few weeks. Henderson has great vision, burst and speed to evade defenders. He has 80 carries for 474 yards and four touchdowns. On Oct. 8, he logged 19 carries for 118 yards and one score.

Junior running back Miyan Williams returned to the field after missing the last two games. Williams is a power runner who stays low to the ground. The Ohio native can barrel his way through many tackles. Williams is leading the team in rushing yards (516) and rushing touchdowns (9). On Oct. 1, he amassed 189 rushing yards and a whopping five scores. 

Why Penn State can cover

Sophomore receiver Parker Washington is the leading pass-catcher for this group. Washington is a smooth catch-and-run threat with reliable hands. The Texas native has a knack for getting open due to his precision and awareness of the field. Washington is leading the team in catches (30) and receiving yards (388). He logged seven grabs for 70 yards and a score in his last outing.

Senior receiver Mitchell Tinsley forms a nice 1-2 combo with Washington. Tinsley is a fluid athlete who gets in and out of his breaks with ease. He can take the top off a defense if needed but is well-rounded. Tinsley is second on the team in receptions (28) and receiving yards (340) but tied for first in receiving touchdowns (4). 

How to make Penn State vs. Ohio State picks

SportsLine's model is leaning Under on the total, projecting a combined 57 points. The model also says one side of the spread hits in almost 60% of simulations. You can only see the model's CFB picks at SportsLine.

So who wins Ohio State vs. Penn State? And which side of the spread hits in almost 60% of simulations? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.