San Diego State looks to start its season off 3-0 as it hosts the UCLA Bruins in a Week 2 Southern California battle on Saturday. The Aztecs are off to a 2-0 start after defeating Ohio 20-13 and Idaho State 36-28. They welcome a Bruins squad to town who are off to a 1-0 start after defeating Coastal Carolina 27-13 in Week 1.

Kickoff is 7:30 p.m. ET on CBS and Paramount+. The Bruins are 13.5-point favorites in the latest San Diego State vs. UCLA odds from the SportsLine consensus, while the over/under for total points scored is 49.5. Before locking in any UCLA vs. San Diego State picks, you need to see the college football predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed the model has seen huge returns.

Now the model has dialed in on UCLA vs. San Diego State and just revealed its coveted picks and predictions. You can head to SportsLine now to see the model's picks. Now, here are the college football odds and trends for San Diego State vs. UCLA: 

  • San Diego State vs. UCLA spread: UCLA -13.5
  • San Diego State vs. UCLA  over/under: 49.5 points 
  • San Diego State vs. UCLA money line: UCLA -571, SDSU +416
  • San Diego State vs. UCLA picks: See picks here
  • San Diego State vs. UCLA streaming: Paramount+

Why UCLA can cover

The Bruins might have looked their most polished in their Week 1 win, but they were able to generate enough offense to pass the Chanticleers. Dante Moore was the more impressive of the two QBs who played in that game and there are calls for Chip Kelly to tap him as QB1 ahead of Saturday's game down in San Diego.

UCLA also has history on its side when it comes to this matchup. The Bruins hold a 22-1-1 record against San Diego State dating back to 1922, with their only loss to the Aztecs occurring in 2019. See picks at SportsLine

Why San Diego State can cover

San Diego State has shown in its first two games this season that it has offensive weapons to reckon with. Starting QB Jalen Mayden is connecting well with Mark Redman as the former Washington TE caught two TD passes in the season opener. Mayden is also currently the team's leading rusher, averaging 9.8 yards through the first two games of the season.

While the Aztecs didn't dominate either of their first two opponents this season, they have certainly shown that they have a strong home-field presence. Expect the home crowd to have their back and push them along with the Bruins visiting from Los Angeles. See picks at SportsLine.  

How to make San Diego State vs. UCLA picks

SportsLine's model is leaning Over on the point total, projecting the teams to combine for 51 points. It also says one side of the spread hits well over 50% of the time. You can see the model's pick at SportsLine

So who wins San Diego State vs. UCLA, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up almost $2,500 on top-rated spread picks since its inception, and find out, and don't forget to stream on Paramount+.