| All Quarterbacks vs Cardinals | |||||||||||||
| Passing | Rushing | ||||||||||||
| Week | Player | Att | Cmp | Yd | TD | Int | Rate | Att | Yd | Avg | TD | FL | FPTS |
| 1 | Herbert, Justin, LAC | 27 | 17 | 209 | 1 | 1 | 83.7 | 5 | 29 | 5.80 | 0 | 0 | 14 |
| 2 | Lock, Drew, SEA | 26 | 19 | 235 | 3 | 0 | 139.1 | 0 | 0 | 0 | 0 | 0 | 27 |
| 3 | Purdy, Brock, SF | 27 | 15 | 297 | 4 | 0 | 133.8 | 2 | 34 | 17.00 | 0 | 0 | 38 |
| 4 | Winston, Jameis, NYG | 29 | 18 | 250 | 3 | 2 | 95.5 | 0 | 0 | 0 | 0 | 0 | 24 |
| 5 | Goff, Jared, DET | 30 | 19 | 271 | 3 | 0 | 125.8 | 1 | 1 | 1.00 | 1 | 0 | 34 |
| 6 | Stafford, Matthew, LAR | 33 | 25 | 222 | 2 | 0 | 113.4 | 0 | 0 | 0 | 0 | 0 | 20 |
| 7 | Nix, Bo, DEN | 29 | 15 | 222 | 1 | 0 | 88.6 | 7 | 73 | 10.43 | 1 | 0 | 27 |
| 8 | Prescott, Dak, DAL | 29 | 19 | 195 | 1 | 0 | 96.2 | 7 | 20 | 2.86 | 1 | 0 | 21 |
| 9 | Lock, Drew, SEA | 28 | 19 | 175 | 1 | 0 | 96.6 | 5 | 16 | 3.20 | 0 | 0 | 14 |