Severino is out of the lineup for Wednesday's game against the Mariners, Roch Kubatko of MASNSports.com reports.

After resting for the second half of Tuesday's doubleheader, Severino will get Wednesday off entirely while Chance Sisco gets another turn behind the plate. Severino still appears locked in as the Orioles' No. 1 catcher.

Trevino isn't in the lineup for Wednesday's game against the Rays, Kennedi Landry of MLB.com reports.

Trevino had gone 5-for-11 with a double, one run, one walk and three strikeouts while starting in each of the past three games. However, Jonah Heim will serve as the starting catcher Wednesday, batting seventh.

Stallings isn't starting Wednesday's game against the Padres.

Stallings had recorded hits in each of his last five starts and went 8-for-16 with three doubles, five RBI, four runs and five walks during that time. Michael Perez will take over behind the dish Wednesday, batting eighth.

Posey isn't starting Wednesday against the Reds, Maria I. Guardado of MLB.com reports.

Posey had started each of the last two games and went 2-for-7 with a run and three strikeouts. Curt Casali will serve as the starting catcher for Wednesday's series finale, batting eighth.

Suzuki isn't starting Wednesday's game against the Royals.

Suzuki had started each of the last two games and went 3-for-4 with a double, one run and one RBI. However, Anthony Bemboom will take over behind the plate Wednesday, batting eighth.

Jansen is out of the lineup for Wednesday's game against the Yankees.

With the Blue Jays and Yankees wrapping up their series with a day game, Jansen will be getting a breather after catching all nine innings of Toronto's 7-3 win Tuesday. Alejandro Kirk will form a battery with T.J. Zeuch in the series finale.

Mancini is out of the lineup for Wednesday's game against the Mariners, Ryan Divish of The Seattle Times reports.

Orioles manager Brandon Hyde will extend Mancini his first off day of the season with the 29-year-old hitting just .159 through the team's first 11 games. Maikel Franco replaces Mancini at first base.

Tsutsugo will serve as the Rays' designated hitter and bat seventh Wednesday against the Rangers.

Tsutsugo had been the Rays' primary leadoff option against right-handed pitching to begin the season, but he appears to have lost hold of that role after providing a .147/.216/.176 slash line through his first 38 plate appearances. For the second straight day, Tsutsugo will hit in the bottom half of the lineup, while Austin Meadows handles leadoff duties.

Pujols will start at first base and bat fifth Wednesday against the Royals.

Due to the Angels' growing injury list, Jared Walsh has been logging more time in right field of late, opening up more reps at first base for Pujols in the process. He'll be in the lineup for a fourth straight game Wednesday after going 5-for-12 with a walk and a run scored in the previous three contests. The Angels should eventually get some reinforcement in the outfield once Justin Upton (back) is available, but Pujols' playing-time outlook could still be relatively strong while Juan Lagares (calf) and Dexter Fowler (knee) are on the shelf.

Walsh will start in right field and bat cleanup Wednesday against the Royals.

With Juan Lagares (calf) recently joining Dexter Fowler (knee) on the injured list and with Justin Upton (back) considered day-to-day, the Angels are running thin on options in the corner outfield. Walsh has been able to pick up more work in right field as a result, as he'll be making his third straight start at the position Wednesday. With four outfield starts in total already under his belt this season, Walsh looks like he could soon gain eligibility at the position in certain fantasy leagues.

Vogelbach will start at first base and bat second Wednesday against the Cubs.

Kolten Wong's (oblique) recent move to the injured list appears to have indirectly opened up a regular spot in the lineup for Vogelbach versus right-handed pitching. In place of Wong, Keston Hiura will pick up his second start at second base in three days Wednesday, allowing Vogelbach to pick up his third start in four days at first base. With his playing time on the rise, Vogelbach could make for an intriguing short-term pickups for fantasy managers looking for power production.

Diaz went 2-for-3 with an RBI single and a walk in a loss to the Rangers on Tuesday.

Diaz owns a stellar .395 on-base percentage thanks in large part to his 15.8 percent walk rate, but he'd otherwise found success at the plate somewhat fleeting prior to Tuesday's production. Diaz has now reached safely in four straight games, but his anemic .323 slugging percentage underscores the fact he only has a pair of doubles in terms of extra-base hits over his first 38 plate appearances.

Moore went 0-for-5 with one strikeout during Tuesday's doubleheader against the Orioles, lowering his season line to .121/.211/.212 over 38 plate appearances.

Moore's early struggles are particularly disappointing when considering he started the season with a chance to potentially take a long-term hold of the everyday job at the keystone with Shed Long still in the final stages of recovery from last year's shin injury. However, a combination of an elevated 34.2 percent strikeout rate and atypically low .190 BABIP have conspired to keep his numbers at their current levels, as has an anemic 19.0 percent hard-hit rate.

Arroyo will start at second base and bat leadoff in the first game of Wednesday's doubleheader with the Twins, Bill Koch of The Providence Journal reports.

With Enrique Hernandez resting for the front end of the twin bill, Arroyo will get his first look of the season to hit out of the leadoff spot. Manager Alex Cora is rewarding Arroyo with the leadoff opportunity after he went 2-for-3 with a double and two runs in Tuesday's 4-2 win. Arroyo has now started in five of the Red Sox's last six games.

Odor will start at second base and bat eighth Wednesday against the Blue Jays, Lindsey Adler of The Athletic reports.

The Yankees have wasted little time working Odor into the mix since acquiring him from the Rangers on April 6. He'll be picking up his fourth straight start at the keystone Wednesday after going 2-for-12 with a pair of RBI through his first three games with the club. New York could end up moving DJ LeMahieu over to first base on a more regular basis if Odor performs well enough at the plate to earn an everyday role.

La Stella went 3-for-3 with a double and a run scored in Tuesday's 7-6 win over the Reds.

La Stella hit a leadoff single in the first inning and scored on Mike Yastrzemski's two-run homer. In the second, La Stella hit his third double of the year but was left on base. Donovan Solano pinch hit for him in the seventh inning. La Stella is 6-for-17 (.353) with two runs scored, no homers, no RBI and no stolen bases in nine games. He was limited by a back injury early in the year, but La Stella could hit his way into a platoon with Solano at second base.

LeMahieu is out of the lineup for Wednesday's game against the Blue Jays, Lindsey Adler of The Athletic reports.

Aaron Hicks will get a turn in the leadoff role while LeMahieu sits for the first time this season. With a .295/.392/.455 slash line through his first 11 starts, LeMahieu has continued to thrive atop the lineup in his third season with the Yankees.

Albies went 2-for-4 with a solo home run and a walk in Tuesday's 14-8 loss to the Marlins.

Albies recorded his first-ever hit off of Pablo Lopez when he took him deep to right in the first for Atlanta's second home run of the inning and gave them an early 3-0 lead. The 24-year-old began the year hitless in his first 19 at-bats but has started to settle in a bit at the plate as of late, as he's registered a hit in six of his last seven games, including two home runs, seven RBI and six runs scored over that span. Manager Brian Snitker also decided to move Albies down to the No. 6 spot in the batting order, and it has proven to be a beneficial move after he recorded his first multi-hit effort of the season in Tuesday's loss to the Marlins.

Tejeda isn't starting Wednesday against the Rays, Kennedi Landry of MLB.com reports.

Tejeda will take a seat for a second straight game after he struck out five times in his last seven at-bats. Charlie Culberson will start at third base and bat eighth against left-hander Josh Fleming on Wednesday.

Longoria isn't in the lineup for Wednesday's game against the Reds, Maria I. Guardado of MLB.com reports.

Longoria went 2-for-4 with a solo home run, two runs and a strikeout in Tuesday's matchup. However, Tommy La Stella will shift to third base for Wednesday's series finale while Donovan Solano starts at second base.

Twins manager Rocco Baldelli said he expects Donaldson (hamstring) to be activated ahead of the second game of Wednesday's doubleheader with the Red Sox, Do-Hyoung Park of MLB.com reports.

Since Donaldson has recently recovered from a right hamstring strain, the Twins weren't keen on having him play both ends of the twin bill, so the team will wait to activate him until the second game to maintain some extra roster flexibility. Assuming Donaldson is in fact activated following the first game, he should step back into a starting role at third base for the nightcap.

Longoria went 2-for-4 with a solo home run and two totals runs scored in Tuesday's 7-6 win over the Reds.

Longoria got aboard with a first-inning single and scored on Brandon Crawford's two-run shot. In the sixth, Longoria added a game-tying solo shot of his own. The third baseman is crushing the ball early in 2021 with a .316/.366/.658 slash line, four homers, eight RBI and six runs scored across 41 plate appearances.

Bryant isn't starting Wednesday's game against the Brewers.

Bryant went 2-for-7 with a home run, two RBI and two runs to begin the series against Milwaukee. However, David Bote will take his place at the hot corner Wednesday while Eric Sogard starts at second base.

The Rays optioned Padlo to their alternate training site Wednesday.

Tampa Bay will demote Padlo to clear a spot on the 26-man active roster for lefty Josh Fleming, who is slated to start Wednesday's game against the Rangers. During his first cup of coffee in the big leagues, Padlo saw action in three games and went hitless with a pair of walks over eight plate appearances.

Gregorius is out of the lineup for Wednesday's game against the Mets.

Gregorius will be getting his first day off after starting in each of the Phillies' first 11 games and batting .317 with two home runs, a stolen base and nine RBI. Ronald Torreyes will replace Gregorius at shortstop and will bat seventh.

Crawford went 3-for-6 with a run while starting both games of Tuesday's doubleheader against the Orioles.

The previously struggling shortstop continued his ascension at the plate with Tuesday's solid day. Crawford had gotten his average up over the Mendoza Line for the first time this season with his first multi-hit effort of the season Sunday, and although all three hits Tuesday were singles, and he's still in search of his first extra-base hit of the campaign, his average is now up to a respectable .256.

Castro isn't starting Wednesday's game against the Astros, Chris McCosky of The Detroit News reports.

Castro had started each of the first 11 games of the season and slashed .196/.229/.239 with a triple, two runs, one RBI and 12 strikeouts. Niko Goodrum will shift to shortstop while Harold Castro starts at second base Wednesday.

Iglesias will bat sixth and start at shortstop Wednesday against the Royals.

Iglesias has started in all 12 of the Angels' games this season, but he'll be batting higher than seventh in the order for only the second time Wednesday. The Angels' growing injury list has contributed to Iglesias' move up the order, and the shortstop has rewarded the team with back-to-back two-hit games to begin the series with Kansas City.

Walton was returned to the Mariners' taxi squad Wednesday.

Walton was called up by Seattle as the 27th man for Tuesday's twin bill against the Orioles, but he failed to appear in either contest. The 26-year-old has appeared in 12 major-league games in the past two seasons and has hit .172 with a double, five RBI and 10 strikeouts.

Simmons was placed on the COVID-19 injured list earlier Wednesday after he tested positive for the coronavirus, Phil Miller of the Minneapolis Star Tribune reports.

According to the Twins, Simmons is currently experiencing "very mild symptoms" of the virus, leaving the club optimistic that he'll be able to make a quick recovery. Per MLB's health and safety protocols, players that test positive for the virus are eligible to return after 10 days in quarantine, so Simmons could be able to rejoin the club as soon as April 24. Look for Jorge Polanco to serve as the Twins' primary shortstop while Simmons recovers from the illness.

Quinn will start in center field and bat eighth Wednesday against the Mets.

Making his third start in four games, Quinn could be in store for an extended run as the Phillies' everyday center fielder after Adam Haseley (personal) was placed on the restricted list Wednesday. Quinn will likely bat near the bottom of the lineup whenever he starts, but he'll have some appeal for fantasy managers in deeper mixed leagues and NL-only formats looking for help in stolen bases. Over his 160 career MLB games, Quinn has gone 37-for-43 in steal attempts.

Inciarte will start in center field and bat eighth Wednesday against the Marlins.

With Atlanta placing Cristian Pache (groin) on the injured list Wednesday, Inciarte looks poised to receive the majority of the starts in center field in the short term. The lefty-hitting Inciarte could end up filling the strong side of a platoon at the position with the right-handed Guillermo Heredia, who was recalled from Atlanta's alternate site after Pache was placed on the IL.

Haniger went 4-for-8 with a double, an RBI and two runs while playing both games of Tuesday's doubleheader against the Orioles.

The veteran pushed his season slash to .311/.327.533 across 49 plate appearances with his productive day. Haniger has reached safely in all 11 games thus far this season, and he's demonstrated his bat speed is close to top form by lacing six (four doubles, two home runs) of his first 14 hits for extra bases.

White isn't starting Wednesday's game against the Rays, Kennedi Landry of MLB.com reports.

White will get a breather after he went 3-for-14 with a triple, two runs and one RBI in the past four games. David Dahl will serve as the designated hitter Wednesday while Adolis Garcia starts in left field.

Haseley was placed on the restricted list for personal reasons Wednesday.

Haseley started in Tuesday's nightcap against the Mets, but he's now away from the team for an undetermined amount of time. Mickey Moniak was recalled by the Phillies in a corresponding move and should serve as outfield depth, while Roman Quinn should take over as the primary center fielder in Haseley's absence.

Moniak was recalled from Triple-A Lehigh Valley on Wednesday.

Moniak was sent to minor-league camp in late March, but he'll rejoin the major-league club after Adam Haseley (personal) was placed on the restricted list. Moniak should serve in a depth role in the outfield with Haseley away from the team indefinitely. Moniak appeared in eight major-league games last year and hit .214 with three runs and six strikeouts in 14 at-bats. Roman Quinn should take over in center field while Haseley is sidelined.

President of baseball operations Jed Hoyer said Hendricks (illness) is feeling better after being scratched ahead of his scheduled start Tuesday against the Brewers, but the Cubs have yet to determine when he'll be ready to rejoin the rotation, Paul Sullivan of the Chicago Tribune reports.

Hendricks was experiencing symptoms of congestion and was scratched out of an abundance of caution, and since leaving Milwaukee to return to Chicago, he's tested negative for COVID-19. Assuming Hendricks continues to test negative over the next couple of days and his condition keeps improving, he may have a chance to rejoin the rotation during this weekend's series with Atlanta. Alec Mills made a spot start for Hendricks on Tuesday and would line up for another turn Sunday if Hendricks can't go.

Webb will pitch out of the bullpen going forward, Alex Pavlovic of NBC Sports Bay Area reports.

Webb made two starts to begin the regular season and posted a 5.23 ERA and 1.94 WHIP in 10.1 innings. However, Alex Wood (back) is slated to make his season debut as a starter Sunday, so Webb will move to a relief role while Aaron Sanchez remains in the starting rotation. Webb should serve as a long reliever for San Francisco but is expected to remain stretched out in case he's needed as a starter at some point, Mark W. Sanchez of KNBR 680 San Francisco reports.

De Leon will pitch out of the bullpen going forward, C. Trent Rosecrans of The Athletic reports.

De Leon served as a member of the starting rotation for his first two appearances and posted a 7.71 ERA and 18:5 K:BB in 9.1 innings to begin the year. However, manager David Bell confirmed Wednesday that De Leon will move to a relief role since Sonny Gray (back) is slated to make his season debut Saturday. De Leon is unlikely to factor into high-leverage situations in the near future.

Gray (back) will start Saturday's game against Cleveland, C. Trent Rosecrans of The Athletic reports.

Gray will make his season debut for the second game of the series against Cleveland after he missed the start of the year due to back spasms. The right-hander threw a successful simulated game Saturday and isn't expected to have a pitch count during Saturday's start, Charlie Goldsmith of The Cincinnati Enquirer reports.

Davidson was recalled by Atlanta on Wednesday.

Davidson was sent to Triple-A Gwinnett in mid-March but will join the major-league bullpen after left-hander Max Fried (hamstring) was placed on the 10-day injured list Wednesday. Davidson allowed two runs on three hits and four walks while striking out two in 1.2 innings during his lone major-league start in 2020.

Atlanta placed Fried on the 10-day injured list Wednesday with a right hamstring strain.

Fried will be sidelined after tweaking his hamstring while running the bases during his start Tuesday against the Marlins. Considering that the young lefty had been roughed up for 13 runs (12 earned) in six innings over his last two starts, the trip to the IL could provide a well-timed break for Fried to get his mechanics right. Tucker Davidson was recalled from Atlanta's alternate site in a corresponding move, but Bryse Wilson could be the top candidate to fill Fried's spot in the rotation.

Bradley (oblique) will miss 3-to-4 weeks, Matt Breen of The Philadelphia Inquirer reports.

Bradley was placed on the 10-day injured list Sunday due to a left oblique strain, and manager Joe Girardi revealed Wednesday that the right-hander will spend more than the minimum of 10 days on the injured list. Prior to his injury, Bradley posted a 6.00 ERA and 1.67 WHIP in three innings across four relief appearances this year.

Romo fired a perfect eighth inning in a win over the Diamondbacks on Tuesday, recording one strikeout.

Tasked with protecting a narrow 6-5 lead, Romo came through with a quick 11-pitch frame that served as a bridge to current closer Lou Trivino in the ninth. Romo is projected to remain in a setup role behind Trivino as Trevor Rosenthal undergoes an extended recovery from thoracic outlet syndrome surgery, and Tuesday's effort was especially encouraging in that it was the first time in four trips to the mound Romo didn't give up a run.

The Reds transferred Lorenzen (shoulder) to the 60-day injured list Wednesday.

Though Cincinnati will soon get a boost in the rotation with Sonny Gray (back) on track to make his season debut Saturday, Lorenzen's ongoing recovery from his injury will leave the team without one of its projected starters until at least late May. The Reds haven't suggested that Lorenzen has hit a setback in his rehab program, but the ramp-up process has been slower than anticipated, as he has yet to get back on a mound since being diagnosed with the strained shoulder late in spring training. Lorenzen's extended absence should give Jeff Hoffman a longer leash as Cincinnati's fifth starter.

Brewer was diagnosed with right shoulder inflammation following a recent bullpen session, Chris Cotillo of The Springfield Republican reports.

Brewer was believed to be a candidate for a promotion to the big club Wednesday to serve as the 27th man for the Red Sox's doubleheader with the Twins, but his injury nixed those plans. Instead, Boston called up reliever Eduard Bazardo.

Wood (back) will start Sunday's game against the Marlins, Alex Pavlovic of NBC Sports Bay Area reports.

Wood made his second rehab start Tuesday, and he'll make his season debut on normal rest for Sunday's series finale against Miami. Wood underwent a minor back procedure in mid-March but allowed just one run on three hits and two walks while striking out two in three innings during two spring starts. Logan Webb will move to a bullpen role with Wood rejoining the starting rotation.

The Red Sox announced that Mata (elbow) underwent Tommy John surgery in Los Angeles on Tuesday, Bill Koch of The Providence Journal reports.

Mata opted for the procedure after he was shut down during spring training when he was diagnosed with a slight tear of the UCL in his right elbow. The 21-year-old is expected to require a 12-to-16-month recovery from the surgery, meaning he'll likely be sidelined until the summer of 2022. Mata had been regarded as one of the Red Sox's top pitching prospects heading into the season.

Ohtani threw a 23-pitch bullpen session Wednesday without a bandage covering his blistered right middle finger, but the Angels have yet to determine when he'll make his next start on the mound, Fabian Ardaya of The Athletic reports.

After throwing a light, 10-pitch bullpen session Monday, Ohtani took a step forward in terms of intensity and volume of pitches Wednesday. The Angels will check back in on Ohtani on Thursday before deciding when to reintegrate him into the rotation, but he won't be an option for this weekend's three-game series versus Minnesota, as the Angels have already penciled in other pitchers to start Friday through Sunday. Ohtani -- who is serving as a designated hitter in Wednesday's series finale with the Royals -- could rejoin the rotation as soon as April 19 versus the Rangers. According to Jeff Fletcher of The Orange County Register, manager Joe Maddon said that whenever Ohtani makes his next start on the mound, his pitch count will likely be "dialed back" as a precaution. Maddon also hinted that Ohtani could be piggybacked in that outing by a long reliever.

Moreland (hamstring) entered Tuesday's win over the Diamondbacks as a pinch hitter in the seventh inning, lacing a single and subsequently scoring in his one plate appearance.

Moreland missed a fourth straight start Tuesday, but the fact he was well enough to pinch hit and then remain in the game once he got on certainly speaks well to the improved health of his balky hamstring. With a team day off Wednesday, Moreland appears to have a reasonably good chance of rejoining the starting nine for the start of a four-game series against the Tigers on Thursday.

Cruz (illness) will serve as the Twins' designated hitter and bat third Wednesday in the first game of Wednesday's doubleheader with the Red Sox, Betsy Helfand of the St. Paul Pioneer Press reports.

Per Do-Hyoung Park of MLB.com, manager Rocco Baldelli said Cruz is feeling "a lot better" after the illness resulted in the veteran slugger being scratched from the lineup ahead of Tuesday's 4-2 loss to Boston. Cruz will put a six-game hit streak on the line as he returns to the lineup for the front end of the twin bill, though it's uncertain whether the Twins will want to have him play in the nightcap while he works his way back from the illness.

Stanton is out of the lineup for Wednesday's game against the Blue Jays, Lindsey Adler of The Athletic reports.

The Yankees will have an off day Thursday, so manager Aaron Boone likely just wanted to build in two days of rest for Stanton by having him sit Wednesday. Since swatting a grand slam April 5 against the Orioles, Stanton has been stuck in a power drought with only one extra-base hit (a double) in 28 at-bats over his subsequent seven starts.

Ohtani went 3-for-5 with a solo home run in Tuesday's loss to the Royals.

Ohtani tagged Danny Duffy for a 431-foot homer in the fifth inning, marking the only run allowed by the Kansas City hurler in the contest. The two-way star also collected a pair of singles for his third multi-hit game over his past five contests. While Ohtani has been able to make only one start on the mound this season, he has shined at the plate, slashing .364/.391/.795 with four homers and 12 RBI across 46 plate appearances.

France went 1-for-4 with a solo home run in a 4-3 win over the Orioles in the first game of Tuesday's doubleheader.

He hammered a John Means pitch to left-center field in the first inning for his second homer of the year. France went 0-for-3 in the nightcap but drew a walk and scored a run, and on the season he sports a .293/.408/.488 slash line through 11 games.