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BYE
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Thu, Dec 17
8:15 pm
AMZN
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11:0349ers vs. Seahawks Preview & Predictions | HQ NFL
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1:56Brock Purdy's MVP Pace Ahead of 49ers vs. Seahawks
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1:30Brock Purdy Thriving Against the Blitz
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1:59Will Lack of RB Depth Hurt Seahawks vs. 49ers?
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1:06Should Brock Purdy Be MVP Favorite Ahead of Josh Allen?
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0:46Fantasy Football Week 5: Start Emanuel Wilson vs. 49ers
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0:36Fantasy Football Week 5: Sit Deebo Samuel at Seahawks
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1:29Seahawks Host Division Rival 49ers in Week 5
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1:32NFL Mock Trades: Josh Sweat to 49ers
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0:3649ers vs. Seahawks: Battle for the NFC Top Spot
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1:19NFL Week 5 Picks: 49ers at Seahawks
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1:23Brock Purdy, 49ers Stay Undefeated Despite Injuries
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1:56Why the 4-0 49ers Don't Need to Lean on McCaffrey
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5:58REACTION: 49ers Outlast Broncos, Improve to 4-0 | HQ NFL
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0:38George Kittle Takes Screen Pass for 49ers Touchdown
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0:26Brock Purdy Finds Deebo Samuel for a 49ers Touchdown
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0:16Broncos Block 49ers' Field Goal Attempt
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0:32Bo Nix Escapes Pressure to Find Tyler Badie vs. 49ers
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1:40Officially Delicious NFL Week 4 Best Bets
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1:31Carhartt Skilled Trades: Tyler Shough or Brock Purdy?
Top 49ers News
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49ers' Jack Stoll: Elevated for Week 5
The 49ers elevated Stoll from the practice squad to the active roster Saturday.
The addition of Stoll gives the 49ers extra depth at tight end behind George Kittle, Luke Farrell and Brayden Willis. Stoll appeared in 15 regular-season games for the Saints in 2025, contributing on both offense and special teams and finishing with six catches on 11 targets for 46 yards and a touchdown.
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49ers' Mykel Williams: In line to make 2026 debut Sunday
The 49ers activated Williams (knee) from the reserve/PUP list Saturday, and he no longer carries an injury designation into Sunday's NFC West tilt against the Seahawks.
Williams is set to play in his first game since he tore his ACL in early November of 2025. It wouldn't be surprising to see the 2025 first-rounder operate under a snap count against Seattle. Nevertheless, the return of Williams is a welcome one for the 49ers, especially with Nick Bosa set to miss a third consecutive game due to a calf injury.
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49ers' James Thompson: Won't play against Seattle
Thompson (ankle) has been ruled out for Sunday's game against the Seahawks.
As expected, Thompson will miss a third consecutive game due to an ankle injury. He didn't practice once during Week 5 prep, so he'll need to return to the field to have a realistic shot of being available for Week 6 against the Commanders on Monday, Oct. 19. Naquan Jones and Sebastian Valdez will both see an uptick in rotational snaps at defensive tackle behind Osa Odighizuwa and Gracen Halton.
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49ers' Mykel Williams: Questionable with ACL injury
Williams (knee) is listed as questionable ahead of Sunday's game against the Seahawks.
The 49ers opened Williams' 21-day practice window Wednesday. The defensive end was limited to start the week before upgrading to a full participant in Friday's practice. With a week of practice under his belt, there is a chance the team could move Williams back to the 53-man roster from the reserve/PUP list in time for Sunday's contest.
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49ers' Upton Stout: Questionable for Sunday
Stout (shoulder) is listed as questionable ahead of Sunday's game against the Seahawks.
Stout is day-to-day with an AC joint sprain. The cornerback practiced in a limited capacity Thursday while missing the 49ers' Wednesday and Friday sessions. Stout has an outside chance to play in Sunday's contest but with one limited practice session during the middle of the week, it is unlikely. If Stout does not play, Ephesians Prysock, Siran Neal or Jack Jones will likely start at slot cornerback against the Seahawks.
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49ers' Nick Bosa: Won't return Week 5
Bosa (calf) has been ruled out ahead of Sunday's game against the Seahawks.
Bosa is hoping to suit up for the 49ers' Week 6 game against the Commanders, Cam Inman of The San Jose Mercury News reports. With the star defensive end still sidelined for the Week 5 divisional showdown, Ogbo Okoronkwo should start against the Seahawks on Sunday.
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49ers' Mike Evans: Cleared for Week 5
Evans (ribs) does not have an injury designation for Sunday's game against the Seahawks, Nick Wagoner of ESPN.com reports.
Evans practiced on a limited basis Wednesday before sitting out Thursday's session, but with him cleared of any injury tag for Week 5 it appears he was simply held out for maintenance purposes. It's unclear just how close Evans is to 100 percent, but he will be out there for his team's key Week 5 matchup with its NFC West rival.
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49ers' Mike Evans: In uniform for Friday's practice
Evans (ribs) was suited up and preparing to take part at the beginning of Friday's practice, Nick Wagoner of ESPN.com reports.
After being limited Wednesday and getting the day off Thursday, Evans appears as if he'll mix into his second session of the week as he guts through a rib injury that he sustained during a Week 3 win against the Cardinals. Friday's practice report will reveal if he has a game designation ahead of Sunday's road matchup with the Seahawks.
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Team Statistical Rankings
| Rushing | Passing | Overall | |
|---|---|---|---|
| Off. |
137.3 (6th) |
251.8 (13th) |
389.0 (7th) |
| Def. |
99.8 (9th) |
214.8 (8th) |
308.8 (7th) |
Injuries
| Player | Injury |
|---|---|
| N. Bosa DE Nick Bosa DE | Calf |
| D. Stribling WR De'Zhaun Stribling WR | Ankle |
| C. Kirk WR Christian Kirk WR | Calf |
| R. Pearsall WR Ricky Pearsall WR | Knee - PCL |
| M. Sigle SAF Marques Sigle SAF | Ankle |
















