| All Quarterbacks vs Jaguars | |||||||||||||
| Passing | Rushing | ||||||||||||
| Week | Player | Att | Cmp | Yd | TD | Int | Rate | Att | Yd | Avg | TD | FL | FPTS |
| 1 | Young, Bryce, CAR | 35 | 18 | 154 | 1 | 2 | 49.0 | 5 | 40 | 8.00 | 0 | 1 | 10 |
| 2 | Browning, Jake, CIN | 32 | 21 | 241 | 2 | 3 | 69.9 | 1 | 1 | 1.00 | 1 | 0 | 21 |
| 2 | Burrow, Joe, CIN | 13 | 7 | 76 | 1 | 0 | 97.0 | 0 | 0 | 0 | 0 | 0 | 9 |
| 3 | Stroud, C.J., HOU | 38 | 25 | 204 | 1 | 2 | 66.1 | 4 | 22 | 5.50 | 0 | 0 | 12 |
| 4 | Purdy, Brock, SF | 38 | 22 | 309 | 2 | 2 | 79.8 | 2 | 13 | 6.50 | 0 | 1 | 21 |
| 5 | Mahomes, Patrick, KC | 41 | 29 | 318 | 1 | 1 | 91.3 | 6 | 60 | 10.00 | 1 | 0 | 28 |
| 6 | Darnold, Sam, SEA | 27 | 16 | 295 | 2 | 0 | 121.7 | 4 | 2 | 0.50 | 0 | 0 | 23 |
| 7 | Stafford, Matthew, LAR | 33 | 21 | 182 | 5 | 0 | 117.7 | 2 | 1 | 0.50 | 0 | 0 | 37 |
| 7 | Garoppolo, Jimmy, LAR | 0 | 0 | 0 | 0 | 0 | 0 | 3 | -3 | -1.00 | 0 | 0 | 0 |
| 9 | Smith, Geno, LV | 39 | 29 | 284 | 4 | 1 | 117.9 | 5 | 9 | 1.80 | 0 | 0 | 33 |
| 10 | Mills, Davis, HOU | 45 | 27 | 292 | 2 | 1 | 84.7 | 3 | 20 | 6.67 | 1 | 0 | 31 |
| 11 | Herbert, Justin, LAC | 18 | 10 | 81 | 0 | 1 | 44.0 | 3 | 21 | 7.00 | 0 | 0 | 3 |
| 11 | Lance, Trey, LAC | 8 | 3 | 37 | 0 | 0 | 52.6 | 3 | 1 | 0.33 | 0 | 0 | 1 |
| 12 | Brissett, Jacoby, ARI | 49 | 33 | 317 | 1 | 0 | 92.0 | 3 | 20 | 6.67 | 0 | 0 | 20 |
| 12 | Slovis, Kedon, ARI | 1 | 1 | -2 | 0 | 0 | 79.2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 13 | Ward, Cam, TEN | 38 | 24 | 141 | 0 | 0 | 70.2 | 1 | 7 | 7.00 | 0 | 0 | 5 |
| 14 | Leonard, Riley, IND | 29 | 18 | 145 | 0 | 1 | 60.3 | 2 | 5 | 2.50 | 1 | 0 | 9 |
| 14 | Jones, Daniel, IND | 7 | 5 | 60 | 0 | 1 | 57.7 | 1 | 4 | 4.00 | 0 | 0 | 0 |