| All Quarterbacks vs Jaguars | |||||||||||||
| Passing | Rushing | ||||||||||||
| Week | Player | Att | Cmp | Yd | TD | Int | Rate | Att | Yd | Avg | TD | FL | FPTS |
| 1 | Watson, Deshaun, CLE | 22 | 16 | 205 | 1 | 1 | 97.7 | 6 | 38 | 6.33 | 0 | 0 | 15 |
| 2 | Nix, Bo, DEN | 31 | 22 | 288 | 1 | 1 | 97.2 | 5 | 6 | 1.20 | 0 | 0 | 15 |
| 3 | Maye, Drake, NE | 25 | 14 | 199 | 0 | 2 | 48.6 | 4 | 18 | 4.50 | 0 | 1 | 2 |
| 3 | DeVito, Tommy, NE | 5 | 3 | 30 | 0 | 0 | 77.1 | 1 | 2 | 2.00 | 0 | 0 | 1 |
| 4 | Burrow, Joe, CIN | 54 | 39 | 428 | 1 | 2 | 86.0 | 3 | 6 | 2.00 | 1 | 0 | 25 |
| 5 | Hurts, Jalen, PHI | 40 | 21 | 220 | 1 | 0 | 77.1 | 2 | 2 | 1.00 | 0 | 0 | 14 |
| 6 | Stroud, C.J., HOU | 34 | 24 | 312 | 3 | 1 | 116.3 | 1 | 5 | 5.00 | 0 | 0 | 28 |
| 8 | Jones, Daniel, IND | 28 | 19 | 144 | 1 | 2 | 62.2 | 4 | 7 | 1.75 | 0 | 0 | 7 |
| 8 | Richardson, Anthony, IND | 2 | 2 | 8 | 0 | 0 | 83.3 | 2 | 4 | 2.00 | 0 | 0 | 0 |
| 9 | Fagnano, Joe, BAL | 18 | 10 | 60 | 0 | 2 | 22.7 | 3 | 13 | 4.33 | 0 | 0 | -1 |