| All Quarterbacks vs Chargers | |||||||||||||
| Passing | Rushing | ||||||||||||
| Week | Player | Att | Cmp | Yd | TD | Int | Rate | Att | Yd | Avg | TD | FL | FPTS |
| 1 | Mahomes, Patrick, KC | 39 | 24 | 258 | 1 | 0 | 89.5 | 6 | 57 | 9.50 | 1 | 0 | 27 |
| 2 | Smith, Geno, LV | 43 | 24 | 180 | 0 | 3 | 37.0 | 5 | 20 | 4.00 | 0 | 0 | 3 |
| 3 | Nix, Bo, DEN | 25 | 14 | 153 | 1 | 0 | 87.6 | 8 | 33 | 4.12 | 0 | 0 | 15 |
| 4 | Dart, Jaxson, NYG | 20 | 13 | 111 | 1 | 0 | 96.0 | 10 | 54 | 5.40 | 1 | 0 | 21 |
| 4 | Wilson, Russell, NYG | 1 | 1 | 8 | 0 | 0 | 100.0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 | Daniels, Jayden, WAS | 26 | 15 | 231 | 1 | 0 | 100.0 | 8 | 39 | 4.88 | 0 | 0 | 18 |
| 6 | Tagovailoa, Tua, MIA | 32 | 21 | 205 | 1 | 3 | 54.8 | 1 | 4 | 4.00 | 0 | 0 | 8 |
| 7 | Jones, Daniel, IND | 34 | 23 | 288 | 2 | 0 | 113.4 | 5 | 7 | 1.40 | 0 | 0 | 25 |
| 8 | Wentz, Carson, MIN | 27 | 15 | 144 | 1 | 1 | 67.5 | 0 | 0 | 0 | 0 | 0 | 9 |
| 8 | Brosmer, Max, MIN | 4 | 3 | 13 | 0 | 0 | 78.1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | Ward, Cam, TEN | 21 | 12 | 145 | 0 | 0 | 78.5 | 2 | 6 | 3.00 | 0 | 0 | 5 |
| 10 | Rodgers, Aaron, PIT | 31 | 16 | 161 | 1 | 2 | 50.6 | 0 | 0 | 0 | 0 | 0 | 8 |
| 11 | Lawrence, Trevor, JAC | 22 | 14 | 153 | 1 | 1 | 80.3 | 5 | 9 | 1.80 | 1 | 0 | 16 |
| 13 | Smith, Geno, LV | 23 | 18 | 165 | 2 | 1 | 107.4 | 2 | -6 | -3.00 | 0 | 0 | 16 |
| 14 | Hurts, Jalen, PHI | 40 | 21 | 240 | 0 | 4 | 31.2 | 4 | 8 | 2.00 | 0 | 1 | -1 |