| All Quarterbacks vs Patriots | |||||||||||||
| Passing | Rushing | ||||||||||||
| Week | Player | Att | Cmp | Yd | TD | Int | Rate | Att | Yd | Avg | TD | FL | FPTS |
| 1 | Lock, Drew, SEA | 22 | 16 | 187 | 1 | 0 | 113.3 | 2 | 13 | 6.50 | 0 | 0 | 14 |
| 1 | Darnold, Sam, SEA | 2 | 1 | 13 | 0 | 0 | 70.8 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2 | Rodgers, Aaron, PIT | 39 | 23 | 187 | 0 | 1 | 60.5 | 1 | 5 | 5.00 | 0 | 1 | 3 |
| 2 | Rudolph, Mason, PIT | 1 | 0 | 0 | 0 | 0 | 39.6 | 1 | 3 | 3.00 | 0 | 0 | 0 |
| 3 | Lawrence, Trevor, JAC | 29 | 19 | 182 | 3 | 1 | 102.9 | 4 | 25 | 6.25 | 0 | 0 | 25 |
| 4 | Allen, Josh, BUF | 33 | 23 | 253 | 1 | 1 | 89.6 | 5 | 4 | 0.80 | 1 | 0 | 20 |
| 5 | Cousins, Kirk, LV | 28 | 19 | 243 | 1 | 0 | 106.7 | 0 | 0 | 0 | 0 | 0 | 15 |
| 5 | Mendoza, Fernando, LV | 8 | 6 | 48 | 0 | 0 | 89.6 | 1 | 3 | 3.00 | 0 | 0 | 1 |
| 6 | Smith, Geno, NYJ | 30 | 20 | 252 | 1 | 1 | 89.9 | 2 | -1 | -0.50 | 0 | 0 | 14 |
| 7 | Williams, Caleb, CHI | 33 | 22 | 308 | 2 | 0 | 116.7 | 5 | 18 | 3.60 | 0 | 0 | 25 |
| 8 | Willis, Malik, MIA | 32 | 21 | 211 | 2 | 1 | 92.1 | 1 | 2 | 2.00 | 0 | 0 | 18 |
| 9 | Love, Jordan, GB | 29 | 23 | 372 | 3 | 0 | 153.2 | 1 | 13 | 13.00 | 1 | 0 | 41 |