| All Quarterbacks vs Titans | |||||||||||||
| Passing | Rushing | ||||||||||||
| Week | Player | Att | Cmp | Yd | TD | Int | Rate | Att | Yd | Avg | TD | FL | FPTS |
| 1 | Nix, Bo, DEN | 40 | 25 | 176 | 1 | 2 | 60.0 | 8 | 18 | 2.25 | 0 | 1 | 8 |
| 2 | Stafford, Matthew, LAR | 33 | 23 | 298 | 2 | 1 | 105.4 | 2 | -6 | -3.00 | 0 | 0 | 21 |
| 3 | Jones, Daniel, IND | 25 | 18 | 228 | 1 | 0 | 113.4 | 4 | 27 | 6.75 | 0 | 0 | 17 |
| 3 | Richardson, Anthony, IND | 0 | 0 | 0 | 0 | 0 | 0 | 4 | -1 | -0.25 | 0 | 0 | 0 |
| 4 | Stroud, C.J., HOU | 28 | 22 | 233 | 2 | 0 | 125.1 | 4 | 11 | 2.75 | 0 | 0 | 22 |
| 5 | Murray, Kyler, ARI | 31 | 23 | 220 | 0 | 0 | 93.5 | 4 | 25 | 6.25 | 1 | 1 | 14 |
| 5 | Brissett, Jacoby, ARI | 1 | 0 | 0 | 0 | 0 | 39.6 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6 | Smith, Geno, LV | 23 | 17 | 174 | 1 | 1 | 91.6 | 4 | -3 | -0.75 | 0 | 0 | 10 |
| 7 | Maye, Drake, NE | 23 | 21 | 222 | 2 | 0 | 135.9 | 8 | 62 | 7.75 | 0 | 0 | 26 |
| 7 | Dobbs, Joshua, NE | 1 | 1 | 12 | 0 | 0 | 116.7 | 2 | -2 | -1.00 | 0 | 0 | 0 |
| 8 | Jones, Daniel, IND | 29 | 21 | 272 | 3 | 0 | 136.0 | 1 | 3 | 3.00 | 0 | 0 | 28 |
| 8 | Leonard, Riley, IND | 2 | 0 | 0 | 0 | 0 | 39.6 | 1 | 1 | 1.00 | 0 | 0 | 0 |
| 9 | Herbert, Justin, LAC | 29 | 19 | 250 | 2 | 1 | 101.2 | 9 | 57 | 6.33 | 1 | 0 | 31 |
| 11 | Mills, Davis, HOU | 41 | 26 | 274 | 1 | 0 | 90.9 | 2 | 14 | 7.00 | 0 | 0 | 17 |
| 12 | Darnold, Sam, SEA | 26 | 16 | 244 | 2 | 0 | 118.1 | 1 | -1 | -1.00 | 0 | 0 | 21 |
| 13 | Lawrence, Trevor, JAC | 27 | 16 | 229 | 2 | 0 | 111.5 | 3 | 25 | 8.33 | 0 | 0 | 25 |
| 13 | Mullens, Nick, JAC | 0 | 0 | 0 | 0 | 0 | 0 | 3 | -3 | -1.00 | 0 | 0 | 0 |
| 14 | Sanders, Shedeur, CLE | 42 | 23 | 364 | 3 | 1 | 97.7 | 3 | 29 | 9.67 | 1 | 0 | 38 |