| All Running Backs vs Cardinals | ||||||||||||
| Rushing | Receiving | |||||||||||
| Week | Player | Att | Yd | Avg | TD | Targt | Recpt | Yd | Avg | TD | FL | FPTS |
| 1 | Hampton, Omarion, LAC | 12 | 43 | 3.58 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 8 |
| 1 | Mitchell, Keaton, LAC | 4 | 9 | 2.25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2 | Wilson, Emanuel, SEA | 21 | 92 | 4.38 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 9 |
| 2 | Price, Jadarian, SEA | 13 | 52 | 4.00 | 0 | 2 | 1 | 8 | 8.00 | 0 | 1 | 3 |
| 2 | Holani, George, SEA | 4 | 13 | 3.25 | 0 | 1 | 1 | 2 | 2.00 | 0 | 0 | 1 |
| 3 | McCaffrey, Christian, SF | 15 | 75 | 5.00 | 1 | 5 | 4 | 41 | 10.25 | 0 | 0 | 17 |
| 3 | Black, Kaelon, SF | 4 | 17 | 4.25 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
| 4 | Skattebo, Cam, NYG | 18 | 58 | 3.22 | 0 | 1 | 1 | 8 | 8.00 | 0 | 0 | 5 |
| 4 | Harris, Najee, NYG | 9 | 30 | 3.33 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3 |
| 4 | Ricard, Patrick, NYG | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 1.00 | 0 | 0 | 0 |
| 4 | Tracy Jr., Tyrone, NYG | 1 | -1 | -1.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 | Gibbs, Jahmyr, DET | 25 | 151 | 6.04 | 2 | 6 | 5 | 56 | 11.20 | 0 | 0 | 32 |
| 5 | Vaki, Sione, DET | 6 | 11 | 1.83 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 6 | Corum, Blake, LAR | 9 | 42 | 4.67 | 0 | 2 | 2 | 18 | 9.00 | 1 | 0 | 11 |
| 6 | Williams, Kyren, LAR | 10 | 50 | 5.00 | 0 | 6 | 3 | 17 | 5.67 | 0 | 0 | 6 |
| 7 | Harvey, RJ, DEN | 3 | 6 | 2.00 | 0 | 2 | 2 | 54 | 27.00 | 1 | 0 | 11 |
| 7 | Dobbins, J.K., DEN | 6 | 23 | 3.83 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 8 |
| 7 | Coleman, Jonah, DEN | 9 | 54 | 6.00 | 0 | 2 | 2 | 15 | 7.50 | 0 | 0 | 6 |
| 8 | Williams, Javonte, DAL | 24 | 56 | 2.33 | 0 | 2 | 1 | 1 | 1.00 | 0 | 0 | 5 |
| 8 | Goodson, Tyler, ATL | 7 | 14 | 2.00 | 0 | 2 | 2 | 19 | 9.50 | 0 | 0 | 2 |
| 9 | Price, Jadarian, SEA | 9 | 24 | 2.67 | 0 | 4 | 4 | 54 | 13.50 | 0 | 0 | 7 |
| 9 | Charbonnet, Zach, SEA | 16 | 77 | 4.81 | 0 | 2 | 1 | 9 | 9.00 | 0 | 0 | 7 |