| All Running Backs vs Panthers | ||||||||||||
| Rushing | Receiving | |||||||||||
| Week | Player | Att | Yd | Avg | TD | Targt | Recpt | Yd | Avg | TD | FL | FPTS |
| 1 | Swift, D'Andre, CHI | 18 | 124 | 6.89 | 3 | 1 | 1 | 10 | 10.00 | 0 | 0 | 31 |
| 1 | Monangai, Kyle, CHI | 10 | 100 | 10.00 | 1 | 2 | 2 | 24 | 12.00 | 0 | 0 | 18 |
| 2 | Robinson, Bijan, ATL | 16 | 72 | 4.50 | 0 | 4 | 3 | 9 | 3.00 | 0 | 0 | 7 |
| 2 | Robinson Jr., Brian, ATL | 11 | 51 | 4.64 | 0 | 2 | 2 | 16 | 8.00 | 0 | 0 | 6 |
| 3 | Judkins, Quinshon, CLE | 18 | 70 | 3.89 | 0 | 2 | 2 | 9 | 4.50 | 0 | 0 | 7 |
| 3 | Sanders, Raheim, CLE | 1 | 17 | 17.00 | 0 | 5 | 4 | 34 | 8.50 | 0 | 0 | 4 |
| 4 | Gibbs, Jahmyr, DET | 15 | 46 | 3.07 | 1 | 7 | 4 | 31 | 7.75 | 0 | 0 | 13 |
| 4 | Vaki, Sione, DET | 0 | 0 | 0 | 0 | 2 | 1 | 17 | 17.00 | 0 | 0 | 1 |
| 6 | Pierce, Dameon, PHI | 12 | 35 | 2.92 | 1 | 5 | 4 | 15 | 3.75 | 0 | 0 | 10 |
| 6 | Steele, Carson, PHI | 0 | 0 | 0 | 0 | 2 | 1 | 4 | 4.00 | 0 | 0 | 0 |
| 7 | Irving, Bucky, TB | 24 | 106 | 4.42 | 2 | 2 | 1 | 4 | 4.00 | 0 | 0 | 22 |
| 7 | Tucker, Sean, TB | 7 | 52 | 7.43 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 11 |
| 7 | Gainwell, Kenneth, TB | 14 | 88 | 6.29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 |
| 8 | Jacobs, Josh, GB | 21 | 39 | 1.86 | 1 | 6 | 6 | 13 | 2.17 | 1 | 0 | 16 |
| 8 | Lloyd, MarShawn, GB | 3 | 7 | 2.33 | 0 | 1 | 1 | 9 | 9.00 | 0 | 0 | 0 |
| 8 | Strong Jr., Pierre, GB | 1 | 2 | 2.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | Coleman, Jonah, DEN | 17 | 57 | 3.35 | 1 | 4 | 4 | 31 | 7.75 | 0 | 0 | 14 |
| 9 | Dobbins, J.K., DEN | 4 | 18 | 4.50 | 0 | 1 | 1 | 4 | 4.00 | 0 | 0 | 1 |