| All Running Backs vs Colts | ||||||||||||
| Rushing | Receiving | |||||||||||
| Week | Player | Att | Yd | Avg | TD | Targt | Recpt | Yd | Avg | TD | FL | FPTS |
| 1 | Henry, Derrick, BAL | 24 | 144 | 6.00 | 3 | 1 | 1 | 19 | 19.00 | 0 | 0 | 33 |
| 1 | Hill, Justice, BAL | 6 | 18 | 3.00 | 0 | 1 | 1 | 10 | 10.00 | 0 | 0 | 2 |
| 2 | Walker III, Kenneth, KC | 24 | 117 | 4.88 | 0 | 10 | 6 | 61 | 10.17 | 0 | 0 | 17 |
| 2 | Johnson, Emmett, KC | 2 | 15 | 7.50 | 0 | 2 | 2 | 20 | 10.00 | 0 | 0 | 3 |
| 3 | Marks, Woody, HOU | 5 | 15 | 3.00 | 1 | 1 | 1 | 6 | 6.00 | 0 | 0 | 7 |
| 3 | Montgomery, David, HOU | 11 | 33 | 3.00 | 0 | 2 | 2 | 15 | 7.50 | 0 | 0 | 4 |
| 4 | Croskey-Merritt, Jacory, WAS | 9 | 15 | 1.67 | 0 | 4 | 2 | 35 | 17.50 | 0 | 0 | 4 |
| 4 | Ekeler, Austin, WAS | 4 | 29 | 7.25 | 0 | 2 | 1 | 11 | 11.00 | 0 | 0 | 3 |
| 4 | Allen, Kaytron, WAS | 3 | 1 | 0.33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 4 | Reynolds, Craig, WAS | 2 | 4 | 2.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 | Warren, Jaylen, PIT | 15 | 101 | 6.73 | 1 | 6 | 6 | 87 | 14.50 | 1 | 0 | 30 |
| 5 | Nichols, Lew, PIT | 1 | 6 | 6.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6 | Pollard, Tony, TEN | 19 | 76 | 4.00 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7 |
| 6 | Spears, Tyjae, TEN | 1 | 1 | 1.00 | 0 | 1 | 1 | 7 | 7.00 | 0 | 0 | 0 |
| 7 | Mason, Jordan, MIN | 15 | 68 | 4.53 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 6 |
| 7 | Jones, Aaron, MIN | 8 | 26 | 3.25 | 0 | 1 | 1 | 0 | 0.00 | 0 | 0 | 2 |
| 8 | Tuten, Bhayshul, JAC | 16 | 104 | 6.50 | 1 | 2 | 2 | 55 | 27.50 | 1 | 0 | 27 |
| 8 | Rodriguez Jr., Chris, JAC | 6 | 41 | 6.83 | 1 | 1 | 1 | 17 | 17.00 | 0 | 0 | 11 |
| 8 | Abdullah, Ameer, JAC | 6 | 13 | 2.17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 9 | Williams, Javonte, DAL | 20 | 101 | 5.05 | 1 | 5 | 4 | 23 | 5.75 | 0 | 0 | 18 |
| 9 | Goodson, Tyler, ATL | 12 | 77 | 6.42 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7 |