| All Running Backs vs Chiefs | ||||||||||||
| Rushing | Receiving | |||||||||||
| Week | Player | Att | Yd | Avg | TD | Targt | Recpt | Yd | Avg | TD | FL | FPTS |
| 1 | Hampton, Omarion, LAC | 15 | 48 | 3.20 | 0 | 2 | 2 | 13 | 6.50 | 0 | 0 | 5 |
| 1 | Harris, Najee, LAC | 1 | 5 | 5.00 | 0 | 1 | 1 | 5 | 5.00 | 0 | 0 | 0 |
| 2 | Barkley, Saquon, PHI | 22 | 88 | 4.00 | 1 | 2 | 2 | 6 | 3.00 | 0 | 0 | 14 |
| 2 | Dillon, AJ, PHI | 3 | 19 | 6.33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 3 | Skattebo, Cam, NYG | 10 | 60 | 6.00 | 1 | 8 | 6 | 61 | 10.17 | 0 | 0 | 18 |
| 3 | Tracy Jr., Tyrone, NYG | 7 | 29 | 4.14 | 0 | 3 | 2 | 7 | 3.50 | 0 | 0 | 2 |
| 3 | Singletary, Devin, NYG | 4 | 11 | 2.75 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 4 | Hill, Justice, BAL | 3 | 76 | 25.33 | 1 | 6 | 5 | 41 | 8.20 | 1 | 0 | 23 |
| 4 | Henry, Derrick, BAL | 8 | 42 | 5.25 | 0 | 3 | 2 | 16 | 8.00 | 0 | 0 | 5 |
| 5 | Etienne, Travis, JAC | 12 | 49 | 4.08 | 0 | 4 | 3 | 9 | 3.00 | 0 | 0 | 4 |
| 5 | Tuten, Bhayshul, JAC | 4 | 6 | 1.50 | 0 | 1 | 1 | 5 | 5.00 | 0 | 0 | 0 |
| 6 | Gibbs, Jahmyr, DET | 17 | 65 | 3.82 | 0 | 2 | 1 | 0 | 0.00 | 0 | 0 | 6 |
| 6 | Montgomery, David, DET | 4 | 24 | 6.00 | 0 | 2 | 2 | 37 | 18.50 | 0 | 0 | 5 |
| 7 | Jeanty, Ashton, LV | 6 | 21 | 3.50 | 0 | 1 | 1 | 13 | 13.00 | 0 | 0 | 3 |
| 7 | Laube, Dylan, LV | 2 | 3 | 1.50 | 0 | 1 | 1 | 1 | 1.00 | 0 | 0 | 0 |
| 7 | Mostert, Raheem, LV | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 2.00 | 0 | 0 | 0 |
| 8 | McNichols, Jeremy, WAS | 1 | 4 | 4.00 | 0 | 6 | 5 | 64 | 12.80 | 0 | 0 | 6 |
| 8 | Croskey-Merritt, Jacory, WAS | 9 | 25 | 2.78 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2 |
| 8 | Rodriguez Jr., Chris, WAS | 1 | 2 | 2.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | Cook, James, BUF | 27 | 114 | 4.22 | 0 | 1 | 1 | 11 | 11.00 | 0 | 0 | 12 |
| 9 | Johnson, Ty, BUF | 2 | 8 | 4.00 | 1 | 2 | 2 | 12 | 6.00 | 0 | 0 | 7 |
| 11 | McLaughlin, Jaleel, DEN | 6 | 19 | 3.17 | 1 | 1 | 1 | -5 | -5.00 | 0 | 0 | 7 |
| 11 | Harvey, RJ, DEN | 11 | 30 | 2.73 | 0 | 3 | 3 | 20 | 6.67 | 0 | 0 | 5 |
| 11 | Prentice, Adam, DEN | 0 | 0 | 0 | 0 | 2 | 1 | 14 | 14.00 | 0 | 0 | 1 |
| 11 | Badie, Tyler, DEN | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0.00 | 0 | 0 | 0 |
| 12 | Taylor, Jonathan, IND | 16 | 58 | 3.62 | 0 | 3 | 2 | 8 | 4.00 | 0 | 0 | 5 |
| 13 | Williams, Javonte, DAL | 17 | 59 | 3.47 | 0 | 3 | 3 | 21 | 7.00 | 1 | 0 | 13 |
| 13 | Davis, Malik, DAL | 3 | 47 | 15.67 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 10 |