| All Running Backs vs Rams | ||||||||||||
| Rushing | Receiving | |||||||||||
| Week | Player | Att | Yd | Avg | TD | Targt | Recpt | Yd | Avg | TD | FL | FPTS |
| 1 | Chubb, Nick, HOU | 13 | 60 | 4.62 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 |
| 1 | Pierce, Dameon, PHI | 3 | 5 | 1.67 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 1 | Marks, Woody, HOU | 3 | 3 | 1.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 1 | Ogunbowale, Dare, HOU | 2 | 9 | 4.50 | 0 | 2 | 2 | 17 | 8.50 | 0 | 1 | -1 |
| 2 | Pollard, Tony, TEN | 20 | 92 | 4.60 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 9 |
| 3 | Barkley, Saquon, PHI | 18 | 46 | 2.56 | 0 | 5 | 4 | 9 | 2.25 | 0 | 0 | 4 |
| 4 | Taylor, Jonathan, IND | 17 | 76 | 4.47 | 0 | 5 | 5 | 20 | 4.00 | 0 | 0 | 9 |
| 4 | Goodson, Tyler, ATL | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0.00 | 0 | 0 | 0 |
| 5 | McCaffrey, Christian, SF | 22 | 57 | 2.59 | 0 | 9 | 8 | 82 | 10.25 | 1 | 0 | 19 |
| 5 | Juszczyk, Kyle, SF | 1 | -1 | -1.00 | 0 | 4 | 3 | 21 | 7.00 | 0 | 0 | 2 |
| 5 | Robinson Jr., Brian, ATL | 5 | 12 | 2.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 6 | Henry, Derrick, BAL | 24 | 122 | 5.08 | 0 | 2 | 1 | 8 | 8.00 | 0 | 0 | 12 |
| 6 | Hill, Justice, BAL | 6 | 16 | 2.67 | 0 | 6 | 5 | 28 | 5.60 | 0 | 0 | 3 |
| 7 | Etienne, Travis, NO | 8 | 44 | 5.50 | 0 | 3 | 1 | 11 | 11.00 | 0 | 0 | 5 |
| 7 | Tuten, Bhayshul, JAC | 5 | 22 | 4.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
| 7 | Allen, LeQuint, JAC | 0 | 0 | 0 | 0 | 1 | 1 | 4 | 4.00 | 0 | 0 | 0 |
| 9 | Neal, Devin, NO | 3 | 11 | 3.67 | 0 | 1 | 1 | 1 | 1.00 | 0 | 0 | 1 |
| 9 | Kamara, Alvin, NO | 6 | 14 | 2.33 | 0 | 3 | 1 | 3 | 3.00 | 0 | 1 | -1 |
| 10 | Robinson Jr., Brian, ATL | 8 | 41 | 5.12 | 1 | 1 | 1 | 4 | 4.00 | 0 | 0 | 10 |
| 10 | McCaffrey, Christian, SF | 12 | 30 | 2.50 | 0 | 10 | 8 | 66 | 8.25 | 0 | 0 | 9 |
| 10 | Juszczyk, Kyle, SF | 0 | 0 | 0 | 0 | 2 | 2 | 8 | 4.00 | 0 | 0 | 0 |
| 11 | Walker III, Kenneth, KC | 16 | 67 | 4.19 | 1 | 3 | 3 | 44 | 14.67 | 0 | 0 | 16 |
| 11 | Charbonnet, Zach, SEA | 11 | 37 | 3.36 | 0 | 2 | 2 | 10 | 5.00 | 0 | 0 | 4 |
| 11 | Holani, George, SEA | 2 | 6 | 3.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 12 | Tucker, Sean, TB | 12 | 42 | 3.50 | 0 | 2 | 1 | 4 | 4.00 | 0 | 0 | 4 |
| 12 | White, Rachaad, WAS | 7 | 38 | 5.43 | 0 | 1 | 1 | 4 | 4.00 | 0 | 0 | 3 |
| 12 | Wright, Owen, TB | 3 | 6 | 2.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 13 | Hubbard, Chuba, CAR | 17 | 83 | 4.88 | 0 | 2 | 2 | 41 | 20.50 | 1 | 0 | 18 |
| 13 | Dowdle, Rico, PIT | 18 | 58 | 3.22 | 0 | 2 | 2 | 21 | 10.50 | 0 | 0 | 7 |
| 13 | Etienne, Trevor, CAR | 0 | 0 | 0 | 0 | 1 | 1 | 4 | 4.00 | 0 | 0 | 0 |
| 14 | Knight, Zonovan, ARI | 7 | 16 | 2.29 | 0 | 6 | 3 | 18 | 6.00 | 0 | 0 | 2 |
| 14 | Carter, Michael, TEN | 3 | 13 | 4.33 | 0 | 4 | 2 | 18 | 9.00 | 0 | 0 | 2 |
| 15 | Montgomery, David, HOU | 7 | 32 | 4.57 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 9 |
| 15 | Gibbs, Jahmyr, DET | 13 | 38 | 2.92 | 0 | 7 | 4 | 20 | 5.00 | 0 | 0 | 5 |
| 16 | Walker III, Kenneth, KC | 11 | 100 | 9.09 | 1 | 3 | 3 | 64 | 21.33 | 0 | 0 | 22 |
| 16 | Charbonnet, Zach, SEA | 9 | 32 | 3.56 | 1 | 4 | 4 | 22 | 5.50 | 0 | 0 | 13 |
| 17 | Robinson, Bijan, ATL | 22 | 195 | 8.86 | 1 | 8 | 5 | 34 | 6.80 | 1 | 0 | 34 |
| 17 | Allgeier, Tyler, ARI | 10 | 23 | 2.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
| 18 | Demercado, Emari, KC | 2 | 29 | 14.50 | 0 | 1 | 1 | 28 | 28.00 | 0 | 0 | 4 |
| 18 | Carter, Michael, TEN | 7 | 18 | 2.57 | 0 | 3 | 3 | 21 | 7.00 | 0 | 0 | 3 |
| 18 | Kiner, Corey, ARI | 3 | 13 | 4.33 | 0 | 3 | 2 | 15 | 7.50 | 0 | 0 | 2 |
| 19 | Hubbard, Chuba, CAR | 13 | 46 | 3.54 | 2 | 4 | 2 | 13 | 6.50 | 0 | 0 | 17 |
| 19 | Dowdle, Rico, PIT | 5 | 9 | 1.80 | 0 | 2 | 1 | 6 | 6.00 | 0 | 0 | 0 |
| 19 | Etienne, Trevor, CAR | 1 | 4 | 4.00 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | -2 |
| 20 | Swift, D'Andre, CHI | 19 | 76 | 4.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7 |
| 20 | Monangai, Kyle, CHI | 13 | 36 | 2.77 | 0 | 4 | 4 | 36 | 9.00 | 0 | 0 | 6 |
| 21 | Walker III, Kenneth, KC | 19 | 62 | 3.26 | 1 | 4 | 4 | 49 | 12.25 | 0 | 0 | 16 |
| 21 | Holani, George, SEA | 3 | 4 | 1.33 | 0 | 4 | 3 | 27 | 9.00 | 0 | 0 | 2 |