| All Running Backs vs Dolphins | ||||||||||||
| Rushing | Receiving | |||||||||||
| Week | Player | Att | Yd | Avg | TD | Targt | Recpt | Yd | Avg | TD | FL | FPTS |
| 1 | Jeanty, Ashton, LV | 23 | 102 | 4.43 | 0 | 6 | 6 | 45 | 7.50 | 2 | 0 | 26 |
| 1 | Washington Jr., Mike, LV | 7 | 41 | 5.86 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 |
| 2 | McCaffrey, Christian, SF | 10 | 23 | 2.30 | 2 | 4 | 4 | 43 | 10.75 | 0 | 0 | 18 |
| 2 | Juszczyk, Kyle, SF | 0 | 0 | 0 | 0 | 2 | 2 | 27 | 13.50 | 1 | 0 | 8 |
| 2 | Black, Kaelon, SF | 7 | 25 | 3.57 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
| 2 | James, Jordan, SF | 4 | 15 | 3.75 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 3 | Walker III, Kenneth, KC | 18 | 70 | 3.89 | 1 | 2 | 2 | 3 | 1.50 | 1 | 0 | 19 |
| 3 | Johnson, Emmett, KC | 6 | 17 | 2.83 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 3 | Smith, Brashard, KC | 0 | 0 | 0 | 0 | 1 | 1 | 4 | 4.00 | 0 | 0 | 0 |
| 4 | Jones, Aaron, MIN | 20 | 94 | 4.70 | 0 | 8 | 4 | 34 | 8.50 | 0 | 0 | 12 |
| 4 | Claiborne, Demond, MIN | 3 | 12 | 4.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 4 | Dallas, DeeJay, JAC | 0 | 0 | 0 | 0 | 1 | 1 | 10 | 10.00 | 0 | 0 | 1 |
| 5 | Perine, Samaje, CIN | 14 | 68 | 4.86 | 0 | 2 | 2 | 10 | 5.00 | 1 | 0 | 13 |
| 5 | Brown, Chase, CIN | 13 | 39 | 3.00 | 0 | 4 | 3 | 21 | 7.00 | 0 | 1 | 3 |