| All Running Backs vs Patriots | ||||||||||||
| Rushing | Receiving | |||||||||||
| Week | Player | Att | Yd | Avg | TD | Targt | Recpt | Yd | Avg | TD | FL | FPTS |
| 1 | Jeanty, Ashton, LV | 19 | 38 | 2.00 | 1 | 2 | 2 | 2 | 1.00 | 0 | 0 | 9 |
| 1 | White, Zamir, LV | 3 | 8 | 2.67 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2 | Achane, De'Von, MIA | 11 | 30 | 2.73 | 0 | 10 | 8 | 92 | 11.50 | 1 | 0 | 18 |
| 2 | Ingold, Alec, LAC | 0 | 0 | 0 | 0 | 2 | 2 | 13 | 6.50 | 0 | 0 | 1 |
| 2 | Gordon II, Ollie, MIA | 1 | 8 | 8.00 | 0 | 1 | 1 | 5 | 5.00 | 0 | 0 | 0 |
| 3 | Gainwell, Kenneth, TB | 4 | 16 | 4.00 | 1 | 1 | 1 | 10 | 10.00 | 0 | 0 | 8 |
| 3 | Warren, Jaylen, PIT | 18 | 47 | 2.61 | 0 | 6 | 5 | 34 | 6.80 | 0 | 0 | 7 |
| 4 | Hubbard, Chuba, CAR | 10 | 49 | 4.90 | 0 | 3 | 3 | 20 | 6.67 | 0 | 0 | 6 |
| 4 | Dowdle, Rico, PIT | 9 | 32 | 3.56 | 0 | 1 | 1 | -2 | -2.00 | 0 | 0 | 3 |
| 4 | Etienne, Trevor, CAR | 7 | 33 | 4.71 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 |
| 5 | Cook, James, BUF | 15 | 49 | 3.27 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4 |
| 5 | Johnson, Ty, BUF | 2 | 10 | 5.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 5 | Davis, Ray, BUF | 2 | 1 | 0.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6 | Kamara, Alvin, NO | 10 | 31 | 3.10 | 0 | 5 | 5 | 45 | 9.00 | 0 | 0 | 7 |
| 6 | Miller, Kendre, NO | 8 | 21 | 2.62 | 0 | 1 | 1 | 11 | 11.00 | 0 | 0 | 3 |
| 7 | Pollard, Tony, TEN | 6 | 18 | 3.00 | 0 | 6 | 6 | 43 | 7.17 | 0 | 0 | 5 |
| 7 | Spears, Tyjae, TEN | 5 | 22 | 4.40 | 0 | 4 | 3 | 18 | 6.00 | 0 | 0 | 3 |
| 8 | Sampson, Dylan, CLE | 3 | 0 | 0.00 | 0 | 6 | 5 | 29 | 5.80 | 0 | 0 | 2 |
| 8 | Judkins, Quinshon, CLE | 9 | 19 | 2.11 | 0 | 3 | 3 | -2 | -0.67 | 0 | 0 | 1 |
| 8 | Ford, Jerome, WAS | 0 | 0 | 0 | 0 | 2 | 1 | -1 | -1.00 | 0 | 0 | 0 |
| 9 | Robinson, Bijan, ATL | 12 | 46 | 3.83 | 0 | 10 | 8 | 50 | 6.25 | 0 | 0 | 9 |
| 9 | Allgeier, Tyler, ARI | 2 | 6 | 3.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 10 | Tucker, Sean, TB | 9 | 53 | 5.89 | 0 | 2 | 1 | -2 | -2.00 | 0 | 0 | 5 |
| 10 | White, Rachaad, WAS | 10 | 38 | 3.80 | 0 | 5 | 5 | 16 | 3.20 | 0 | 0 | 4 |
| 11 | Hall, Breece, NYJ | 14 | 58 | 4.14 | 0 | 2 | 2 | 6 | 3.00 | 0 | 0 | 5 |
| 11 | Davis, Isaiah, NYJ | 2 | 11 | 5.50 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
| 12 | Brown, Chase, CIN | 19 | 107 | 5.63 | 0 | 4 | 2 | 23 | 11.50 | 0 | 0 | 12 |
| 12 | Brooks, Tahj, CIN | 2 | 5 | 2.50 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 13 | Singletary, Devin, NYG | 12 | 68 | 5.67 | 1 | 3 | 3 | 34 | 11.33 | 0 | 0 | 15 |
| 13 | Tracy Jr., Tyrone, NYG | 10 | 36 | 3.60 | 0 | 1 | 1 | -3 | -3.00 | 0 | 0 | 3 |
| 15 | Cook, James, BUF | 22 | 107 | 4.86 | 2 | 3 | 2 | 4 | 2.00 | 1 | 0 | 28 |
| 15 | Johnson, Ty, BUF | 4 | 13 | 3.25 | 0 | 3 | 3 | 15 | 5.00 | 0 | 0 | 2 |
| 15 | Davis, Ray, BUF | 0 | 0 | 0 | 0 | 1 | 1 | 13 | 13.00 | 0 | 0 | 1 |
| 16 | Henry, Derrick, BAL | 18 | 128 | 7.11 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 22 |
| 16 | Mitchell, Keaton, LAC | 9 | 13 | 1.44 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 16 | Ali, Rasheen, BAL | 0 | 0 | 0 | 0 | 2 | 2 | 2 | 1.00 | 0 | 0 | 0 |
| 17 | Hall, Breece, NYJ | 14 | 111 | 7.93 | 1 | 3 | 2 | 18 | 9.00 | 0 | 0 | 18 |
| 17 | Nwangwu, Kene, NYJ | 6 | 31 | 5.17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 |
| 17 | Davis, Isaiah, NYJ | 3 | 11 | 3.67 | 0 | 1 | 1 | 9 | 9.00 | 0 | 0 | 1 |
| 17 | Herbert, Khalil, NYJ | 2 | 5 | 2.50 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 18 | Wright, Jaylen, MIA | 13 | 23 | 1.77 | 0 | 2 | 2 | 17 | 8.50 | 0 | 1 | 1 |
| 18 | Ingold, Alec, LAC | 0 | 0 | 0 | 0 | 2 | 1 | 3 | 3.00 | 0 | 0 | 0 |
| 18 | Gordon II, Ollie, MIA | 9 | 9 | 1.00 | 0 | 1 | 1 | 2 | 2.00 | 0 | 0 | 0 |
| 19 | Vidal, Kimani, LAC | 11 | 31 | 2.82 | 0 | 3 | 2 | 20 | 10.00 | 0 | 0 | 5 |
| 19 | Hampton, Omarion, LAC | 1 | -1 | -1.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20 | Chubb, Nick, HOU | 4 | 14 | 3.50 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
| 20 | Marks, Woody, HOU | 14 | 17 | 1.21 | 0 | 3 | 2 | 19 | 9.50 | 0 | 1 | 0 |
| 21 | Harvey, RJ, DEN | 13 | 37 | 2.85 | 0 | 6 | 4 | 22 | 5.50 | 0 | 0 | 5 |
| 21 | McLaughlin, Jaleel, DEN | 4 | 11 | 2.75 | 0 | 2 | 1 | 2 | 2.00 | 0 | 0 | 1 |
| 21 | Prentice, Adam, DEN | 1 | 3 | 3.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 21 | Badie, Tyler, DEN | 1 | 4 | 4.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22 | Walker III, Kenneth, KC | 27 | 135 | 5.00 | 0 | 4 | 2 | 26 | 13.00 | 0 | 0 | 15 |
| 22 | Holani, George, SEA | 2 | 6 | 3.00 | 0 | 1 | 1 | 7 | 7.00 | 0 | 0 | 0 |
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