| All Running Backs vs Giants | ||||||||||||
| Rushing | Receiving | |||||||||||
| Week | Player | Att | Yd | Avg | TD | Targt | Recpt | Yd | Avg | TD | FL | FPTS |
| 1 | Jones, Aaron, MIN | 14 | 94 | 6.71 | 1 | 2 | 2 | 15 | 7.50 | 0 | 0 | 16 |
| 1 | Chandler, Ty, MIN | 8 | 17 | 2.12 | 0 | 3 | 3 | 25 | 8.33 | 0 | 0 | 3 |
| 1 | Gaskin, Myles, JAC | 1 | -3 | -3.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 1 | Ham, C.J., MIN | 0 | 0 | 0 | 0 | 2 | 2 | 11 | 5.50 | 0 | 1 | -1 |
| 2 | Robinson Jr., Brian, WAS | 17 | 133 | 7.82 | 0 | 3 | 1 | 3 | 3.00 | 0 | 0 | 13 |
| 2 | Ekeler, Austin, WAS | 8 | 38 | 4.75 | 0 | 3 | 3 | 47 | 15.67 | 0 | 0 | 7 |
| 3 | Ford, Jerome, CLE | 10 | 37 | 3.70 | 0 | 4 | 3 | 33 | 11.00 | 0 | 0 | 6 |
| 3 | Foreman, D'Onta, CLE | 2 | 5 | 2.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 4 | Dowdle, Rico, DAL | 11 | 46 | 4.18 | 0 | 1 | 1 | 15 | 15.00 | 1 | 0 | 11 |
| 4 | Elliott, Ezekiel, LAC | 5 | 19 | 3.80 | 0 | 1 | 1 | 5 | 5.00 | 0 | 0 | 1 |
| 4 | Luepke, Hunter, DAL | 2 | 8 | 4.00 | 0 | 2 | 2 | 14 | 7.00 | 0 | 0 | 1 |
| 5 | Walker III, Kenneth, SEA | 5 | 19 | 3.80 | 0 | 8 | 7 | 57 | 8.14 | 0 | 0 | 6 |
| 5 | Charbonnet, Zach, SEA | 2 | 11 | 5.50 | 0 | 5 | 3 | 19 | 6.33 | 0 | 0 | 2 |
| 6 | Brown, Chase, CIN | 10 | 53 | 5.30 | 1 | 3 | 2 | 11 | 5.50 | 0 | 0 | 12 |
| 6 | Moss, Zack, CIN | 6 | 13 | 2.17 | 0 | 1 | 1 | 2 | 2.00 | 0 | 1 | -1 |
| 7 | Barkley, Saquon, PHI | 17 | 176 | 10.35 | 1 | 3 | 2 | 11 | 5.50 | 0 | 0 | 24 |
| 7 | Gainwell, Kenneth, PHI | 13 | 56 | 4.31 | 0 | 1 | 1 | 11 | 11.00 | 0 | 0 | 6 |
| 7 | Shipley, Will, PHI | 8 | 15 | 1.88 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 8 | Harris, Najee, PIT | 19 | 114 | 6.00 | 0 | 4 | 3 | 17 | 5.67 | 0 | 0 | 12 |
| 8 | Warren, Jaylen, PIT | 9 | 46 | 5.11 | 0 | 3 | 2 | 13 | 6.50 | 0 | 0 | 5 |
| 9 | Ekeler, Austin, WAS | 11 | 42 | 3.82 | 1 | 4 | 3 | 41 | 13.67 | 0 | 0 | 14 |
| 9 | Rodriguez Jr., Chris, WAS | 11 | 52 | 4.73 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 |
| 9 | McNichols, Jeremy, WAS | 8 | 20 | 2.50 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2 |
| 10 | Hubbard, Chuba, CAR | 28 | 153 | 5.46 | 1 | 6 | 4 | 16 | 4.00 | 0 | 1 | 20 |
| 10 | Sanders, Miles, CAR | 2 | 5 | 2.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 12 | Irving, Bucky, TB | 12 | 88 | 7.33 | 1 | 6 | 6 | 64 | 10.67 | 0 | 0 | 20 |
| 12 | White, Rachaad, TB | 12 | 37 | 3.08 | 1 | 1 | 1 | 10 | 10.00 | 0 | 0 | 10 |
| 12 | Tucker, Sean, TB | 4 | 3 | 0.75 | 1 | 1 | 1 | 7 | 7.00 | 0 | 0 | 6 |
| 13 | Dowdle, Rico, DAL | 22 | 112 | 5.09 | 1 | 3 | 3 | 11 | 3.67 | 0 | 0 | 18 |
| 13 | Luepke, Hunter, DAL | 3 | 4 | 1.33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 13 | Elliott, Ezekiel, LAC | 1 | 4 | 4.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 14 | Miller, Kendre, NO | 10 | 32 | 3.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 9 |
| 14 | Kamara, Alvin, NO | 17 | 44 | 2.59 | 0 | 5 | 5 | 35 | 7.00 | 0 | 0 | 7 |
| 14 | Williams, Jamaal, NO | 3 | 5 | 1.67 | 0 | 2 | 2 | 10 | 5.00 | 0 | 0 | 1 |
| 15 | Hill, Justice, BAL | 2 | 7 | 3.50 | 0 | 5 | 5 | 61 | 12.20 | 1 | 0 | 12 |
| 15 | Henry, Derrick, BAL | 14 | 67 | 4.79 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 |
| 15 | Ali, Rasheen, BAL | 8 | 32 | 4.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 |
| 16 | Robinson, Bijan, ATL | 22 | 94 | 4.27 | 2 | 2 | 2 | 9 | 4.50 | 0 | 0 | 21 |
| 16 | Allgeier, Tyler, ATL | 11 | 22 | 2.00 | 0 | 1 | 1 | 9 | 9.00 | 0 | 0 | 2 |
| 17 | Taylor, Jonathan, IND | 32 | 125 | 3.91 | 2 | 4 | 2 | 11 | 5.50 | 0 | 0 | 25 |
| 17 | Sermon, Trey, IND | 0 | 0 | 0 | 0 | 1 | 1 | 10 | 10.00 | 0 | 0 | 1 |
| 18 | Shipley, Will, PHI | 10 | 32 | 3.20 | 0 | 4 | 4 | 35 | 8.75 | 0 | 0 | 6 |
| 18 | Gainwell, Kenneth, PHI | 11 | 14 | 1.27 | 0 | 4 | 2 | 9 | 4.50 | 0 | 0 | 1 |