| All Running Backs vs Giants | ||||||||||||
| Rushing | Receiving | |||||||||||
| Week | Player | Att | Yd | Avg | TD | Targt | Recpt | Yd | Avg | TD | FL | FPTS |
| 1 | Croskey-Merritt, Jacory, WAS | 10 | 82 | 8.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 14 |
| 1 | Ekeler, Austin, WAS | 6 | 26 | 4.33 | 0 | 3 | 3 | 31 | 10.33 | 0 | 0 | 5 |
| 1 | McNichols, Jeremy, WAS | 4 | 25 | 6.25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
| 2 | Williams, Javonte, DAL | 18 | 97 | 5.39 | 1 | 7 | 6 | 33 | 5.50 | 0 | 0 | 18 |
| 2 | Sanders, Miles, DAL | 5 | 15 | 3.00 | 1 | 2 | 2 | 4 | 2.00 | 0 | 0 | 7 |
| 3 | Hunt, Kareem, KC | 10 | 34 | 3.40 | 1 | 1 | 1 | 10 | 10.00 | 0 | 0 | 10 |
| 3 | Pacheco, Isiah, DET | 10 | 45 | 4.50 | 0 | 1 | 1 | 3 | 3.00 | 0 | 0 | 4 |
| 3 | Smith, Brashard, KC | 2 | 13 | 6.50 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
| 4 | Hampton, Omarion, LAC | 12 | 128 | 10.67 | 1 | 5 | 5 | 37 | 7.40 | 0 | 0 | 21 |
| 5 | Miller, Kendre, NO | 10 | 41 | 4.10 | 0 | 1 | 1 | 8 | 8.00 | 0 | 0 | 4 |
| 5 | Kamara, Alvin, NO | 8 | 27 | 3.38 | 0 | 6 | 4 | 28 | 7.00 | 0 | 0 | 4 |
| 6 | Barkley, Saquon, PHI | 12 | 58 | 4.83 | 0 | 3 | 2 | 9 | 4.50 | 0 | 0 | 5 |
| 6 | Dillon, AJ, CAR | 1 | 2 | 2.00 | 0 | 2 | 2 | 18 | 9.00 | 0 | 1 | -1 |
| 7 | Dobbins, J.K., DEN | 14 | 81 | 5.79 | 0 | 1 | 1 | -1 | -1.00 | 0 | 0 | 8 |
| 7 | Harvey, RJ, DEN | 4 | 0 | 0.00 | 0 | 2 | 1 | 2 | 2.00 | 1 | 0 | 6 |
| 7 | Badie, Tyler, DEN | 0 | 0 | 0 | 0 | 2 | 2 | 19 | 9.50 | 0 | 0 | 1 |
| 8 | Barkley, Saquon, PHI | 14 | 150 | 10.71 | 1 | 5 | 4 | 24 | 6.00 | 1 | 0 | 29 |
| 8 | Bigsby, Tank, PHI | 9 | 104 | 11.56 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10 |
| 8 | Shipley, Will, PHI | 3 | 2 | 0.67 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | McCaffrey, Christian, SF | 28 | 106 | 3.79 | 1 | 6 | 5 | 67 | 13.40 | 1 | 0 | 28 |
| 9 | Robinson Jr., Brian, ATL | 5 | 53 | 10.60 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 11 |
| 9 | Juszczyk, Kyle, SF | 0 | 0 | 0 | 0 | 2 | 1 | 12 | 12.00 | 0 | 0 | 1 |
| 10 | Swift, D'Andre, CHI | 13 | 80 | 6.15 | 0 | 8 | 5 | 18 | 3.60 | 0 | 0 | 9 |
| 10 | Monangai, Kyle, CHI | 7 | 28 | 4.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 8 |
| 11 | Wilson, Emanuel, SEA | 11 | 40 | 3.64 | 1 | 1 | 1 | 9 | 9.00 | 0 | 0 | 12 |
| 11 | Jacobs, Josh, GB | 7 | 40 | 5.71 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4 |
| 11 | Brooks, Christopher, GB | 1 | 8 | 8.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 12 | Gibbs, Jahmyr, DET | 15 | 219 | 14.60 | 2 | 12 | 11 | 45 | 4.09 | 1 | 0 | 43 |
| 12 | Montgomery, David, HOU | 5 | 18 | 3.60 | 0 | 3 | 3 | 19 | 6.33 | 0 | 0 | 2 |
| 13 | Stevenson, Rhamondre, NE | 12 | 40 | 3.33 | 0 | 3 | 3 | 40 | 13.33 | 0 | 0 | 8 |
| 13 | Henderson, TreVeyon, NE | 11 | 67 | 6.09 | 0 | 4 | 3 | 19 | 6.33 | 0 | 0 | 7 |
| 15 | Croskey-Merritt, Jacory, WAS | 18 | 96 | 5.33 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 15 |
| 15 | McNichols, Jeremy, WAS | 9 | 6 | 0.67 | 0 | 1 | 1 | 16 | 16.00 | 0 | 1 | -1 |
| 16 | Jones, Aaron, MIN | 21 | 85 | 4.05 | 0 | 3 | 2 | 8 | 4.00 | 0 | 0 | 8 |
| 16 | Mason, Jordan, MIN | 2 | 5 | 2.50 | 0 | 1 | 1 | 6 | 6.00 | 0 | 0 | 0 |
| 16 | Scott, Zavier, MIN | 2 | 4 | 2.00 | 0 | 1 | 1 | 8 | 8.00 | 0 | 0 | 0 |
| 16 | Ham, C.J., MIN | 1 | 3 | 3.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 17 | Jeanty, Ashton, LV | 16 | 60 | 3.75 | 0 | 2 | 2 | 13 | 6.50 | 0 | 0 | 7 |
| 17 | White, Zamir, LV | 1 | 2 | 2.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 18 | Blue, Jaydon, DAL | 16 | 64 | 4.00 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 12 |
| 18 | Mafah, Phil, DAL | 5 | 18 | 3.60 | 1 | 2 | 2 | 11 | 5.50 | 0 | 0 | 8 |
| 18 | Luepke, Hunter, DAL | 2 | 12 | 6.00 | 0 | 1 | 1 | 4 | 4.00 | 0 | 0 | 1 |