| All Running Backs vs Titans | ||||||||||||
| Rushing | Receiving | |||||||||||
| Week | Player | Att | Yd | Avg | TD | Targt | Recpt | Yd | Avg | TD | FL | FPTS |
| 1 | Hall, Breece, NYJ | 22 | 102 | 4.64 | 1 | 2 | 2 | 16 | 8.00 | 0 | 0 | 17 |
| 1 | Allen, Braelon, NYJ | 10 | 40 | 4.00 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4 |
| 2 | Bigsby, Tank, PHI | 13 | 33 | 2.54 | 1 | 2 | 2 | 5 | 2.50 | 0 | 0 | 9 |
| 2 | Shipley, Will, PHI | 7 | 24 | 3.43 | 0 | 2 | 2 | 5 | 2.50 | 0 | 0 | 2 |
| 2 | Barkley, Saquon, PHI | 4 | 9 | 2.25 | 0 | 2 | 1 | 11 | 11.00 | 0 | 0 | 1 |
| 3 | Skattebo, Cam, NYG | 20 | 60 | 3.00 | 0 | 4 | 3 | 40 | 13.33 | 0 | 0 | 10 |
| 3 | Harris, Najee, NYG | 9 | 52 | 5.78 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 |
| 3 | Tracy Jr., Tyrone, NYG | 1 | 3 | 3.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 4 | Henry, Derrick, BAL | 23 | 73 | 3.17 | 1 | 2 | 2 | 6 | 3.00 | 0 | 0 | 13 |
| 4 | Hill, Justice, BAL | 1 | 3 | 3.00 | 0 | 3 | 2 | 22 | 11.00 | 0 | 0 | 2 |
| 5 | Marks, Woody, HOU | 15 | 62 | 4.13 | 0 | 4 | 4 | 23 | 5.75 | 0 | 0 | 8 |
| 5 | Montgomery, David, HOU | 5 | 11 | 2.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 6 | Taylor, Jonathan, IND | 21 | 94 | 4.48 | 1 | 4 | 2 | 57 | 28.50 | 0 | 1 | 18 |
| 6 | McGowan, Seth, IND | 4 | 27 | 6.75 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |