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Two familiar foes will square off Wednesday when AC Milan host Napoli in the first leg of their Champions League quarterfinal knockout tie on Paramount+. After dominating Eintracht Frankfurt in the Round of 16, Napoli advanced to the Champions League quarterfinals for the first time in the club's history. However, Napoli suffered a shocking 4-0 defeat against AC Milan in Italian Serie A play on April 2.  

Kickoff from the San Siro in Milan is set for 3 p.m. ET. The latest AC Milan vs. Napoli odds from Caesars Sportsbook list Napoli as the +155 favorites (risk $100 to win $155) on the 90-minute money line, with AC Milan as the +180 underdogs. A draw is priced at +220 and the over/under for total goals is 2.5. Wednesday's match will be streamed live on Paramount+ with their must-have Premium plan, which you can try free for seven days and watch over 2,400 soccer matches a year.

Paramount+ is the only place to watch every minute of every Champions League match this season. A subscription also gives you access to other sports content including the Italian Serie A and Europa League, NWSL, NFL on CBS, and countless movies and shows. You can get started with a free seven-day trial, so sign up here

How to watch AC Milan vs. Napoli

  • Napoli vs. AC Milan date: Wednesday, April 12
  • Napoli vs. AC Milan time: 3 p.m. ET
  • Napoli vs. AC Milan live stream: Paramount+ (try free for one week)

UEFA Champions League picks for AC Milan vs. Napoli

Before you tune in to Wednesday's match, you need to see the UEFA Champions League picks from betting expert Brandt Sutton. Sutton, a former collegiate soccer player, has been SportsLine's top soccer editor for more than five years. He has followed soccer closely for much longer and factors in managerial tactics, projected lineups and past performances to make the most-informed decisions possible, keeping his finger on the pulse of the game all over the globe. 

Sutton finished 2022 as SportsLine's top soccer expert with a 165-130-2 mark, returning nearly $2,200 for $100 players. He also excelled in Serie A with a 63-39-1 mark, returning nearly $1,600.

For Napoli vs. AC Milan, Sutton is backing a draw after 30 minutes of play for a -155 payout. Both teams have been stellar defensively in the Champions League this season. In fact, Napoli have recorded a clean sheet in three of their last four fixtures in this competition. Meanwhile, AC Milan have posted a shutout in four straight Champions League matches.

Napoli are also expected to be without their star striker Victor Osimhen on Wednesday. Osimhen, who's recorded 21 goals and four assists in 23 Serie A matches this season, is dealing with an injury that has kept him off the pitch for Napoli's last two games.

"With Osimhen sidelined, I can see Napoli sitting back defensively and making things extremely difficult for AC Milan's attack," Sutton told SportsLine.

Plus, AC Milan have scored more than one goal just twice in their last six Champions League fixtures, another reason why the expert is predicting a cagey affair when these two Italian giants collide on Wednesday. Stream the game here.

How to watch, live stream Champions League on Paramount+

Now that you know what to pick, get ready to watch the UEFA Champions League. Visit Paramount+ now to see UEFA Champions League, your live local CBS sporting events, some of the world's top soccer matchups and much more. Don't forget you can try it free for the first week.