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Reigning Premier League champion Manchester City can join Arsenal atop the EPL table when the two clubs collide in a scintillating showdown on Wednesday at Emirates Stadium in London. Once trailing Arsenal by seven points, Manchester City enter Wednesday's match with 48 points, just three points behind the league-leading Gunners. A win would bring Manchester City level with Arsenal atop the table, though the Gunners still have a game in hand. The teams will play once more this season, on April 26 in Manchester.

Kickoff is at 2:30 p.m. ET. Caesars Sportsbook lists Man City as the +140 favorites (risk $100 to win $140) in the latest Manchester City vs. Arsenal odds, with the Gunners the +195 underdog. A draw is priced at +225. The over/under for total goals scored is 2.5. Before locking in any Arsenal vs. Manchester City picks, you need to see the EPL predictions from SportsLine's proven soccer insider Martin Green.

After working in the sports betting industry for several years, Green became a professional sports writer and handicapper and has covered the game worldwide. Since then, his European soccer picks have been spot-on. Green has generated almost $33,000 for $100 bettors since the 2017-18 season, and he has his finger on the pulse of the game all over the globe.

Now, Green has broken down Man City vs. Arsenal from every angle and just revealed his picks and predictions. You can head to SportsLine now to see Green's picks. Here are the betting lines and trends for Arsenal vs. Man City:

  • Manchester City vs. Arsenal spread: Manchester City -0.5 (+125), Arsenal +0.5 (-160)
  • Manchester City vs. Arsenal over/under: 2.5 goals
  • Manchester City vs. Arsenal money line: Manchester City +140, Arsenal +195, Draw +225
  • MCY: Erling Haaland leads the league in goals (25)
  • ARS: The Gunners rank second in the EPL in goals conceded (18)
  • Manchester City vs. Arsenal picks: See picks here

Why you should back Manchester City

Manchester City have dominated the head-to-head series against Arsenal recently. In fact, City have won the last 10 Premier League meetings against the Gunners, outscoring them 26-3 over that period. Manchester City have not lost a Premier League match to Arsenal since December 2015.

Led by Kevin De Bruyne, Bernardo Silva, Jack Grealish and Riyad Mahrez, City also have the experience of playing in big games like this one. City have won four of the past five Premier League titles, including last year's. On Wednesday. City will face an Arsenal side that is unfamiliar with this setting.

Why you should back Arsenal

The Gunners have a potentially advantageous matchup on the wings with Bukayo Saka on the right and Gabriel Martinelli on the left. Both Saka and Martinelli are tied for second on the team with seven goals this season and are heavily involved in the attacking third. On Wednesday, they could take advantage of a Manchester City side that forgoes the use of traditional fullbacks in build-up.

In addition, Martin Odegaard is having the best season of his career. The 24-year-old midfielder from Norway already has eight goals and five assists in 20 appearances this season. His previous career highs were nine and 12, respectively, in 35 matches with Vitesse in 2018-19.

How to make Arsenal vs. Manchester City picks

Green has taken an in-depth look at the Arsenal vs. Manchester City match from every possible angle. He is leaning Over on the goal total and has locked in two confident best bets, including one that pays plus-money. Head to SportsLine to see his analysis and top picks.

So who wins Manchester City vs. Arsenal on Wednesday? And where does all the betting value lie? Visit SportsLine now to find out which wagers in Arsenal vs. Manchester City have all the value, all from the soccer expert who has generated almost $33,000 for $100 bettors since the 2017-18 season, and find out.