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Manchester City attempt to avenge last year's setback when they begin their 2022-23 UEFA Champions League semifinal tie against Real Madrid on Tuesday. Manchester City faced Real Madrid in the UCL semifinals last season and posted a 4-3 victory in the first leg but dropped the second leg 3-1 and lost the matchup on aggregate. The Citizens knocked off Bayern Munich in this year's quarterfinals, while Los Blancos cruised past Chelsea.

Kickoff at the Santiago Bernabeu is set for 3 p.m. ET on Paramount+. Manchester City are the +114 favorites (risk $100 to win $114) in the latest Manchester City vs. Real Madrid odds from Caesars Sportsbook, while Real Madrid are +220 underdogs. A 90-minute draw is priced at +255 and the over/under for total goals scored is 2.5. Before locking in any Real Madrid vs. Manchester City picks, you need to see the UEFA Champions League predictions from SportsLine's Jon Eimer.

Eimer is a high-volume bettor who has vast knowledge of leagues and players across the globe. Since joining SportsLine, Eimer has covered the English Premier League, Serie A, the FA Cup and much more. Since the end of last year's World Cup, he has been red-hot, going 112-77-6 for a profit of $3,800 for $100 bettors. Anyone following him is way up.

Now, Eimer has broken down Man City vs. Real Madrid from every angle and just revealed his Champions League picks and predictions. You can head to SportsLine now to see Eimer's picks. Here are the betting lines and trends for Real Madrid vs. Man City:

  • Manchester City vs. Real Madrid money line: Man City +114, Real Madrid +220, Draw +255
  • Manchester City vs. Real Madrid over/under: 2.5 goals
  • Manchester City vs. Real Madrid spread: Man City -0.5 (+115)
  • MCY: The Citizens are unbeaten in their last 20 matches across all competitions (17 wins, three draws)
  • RMA: Los Blancos have conceded in four straight games across all competitions
  • Manchester City vs. Real Madrid picks: See picks at SportsLine

Why you should back Manchester City

The Citizens will be facing a Real Madrid side that is without its top defender in Eder Militao, who is serving a suspension. Los Blancos have struggled even with the 25-year-old Brazilian on the pitch, allowing nine goals over their last four matches across all competitions. That is great news for a Man City club that has netted at least three goals in nine of its last 12 overall contests.

Real Madrid's defenders certainly will have their hands full with Erling Haaland, who is having an incredible campaign. The 22-year-old Norwegian striker has set the Premier League single-season record with 35 goals and also leads the Champions League with 12 goals in eight games. Haaland has converted in 11 of his last 14 matches across all competitions and has recorded seven goals over his past three UCL contests, including five in the second leg of the Citizens' Round of 16 tie against RB LeipzigSee who to back at SportsLine

Why you should back Real Madrid

Los Blancos have won five consecutive matches in the competition, outscoring their opponents 15-3 during the streak. They have posted three straight clean sheets as they recorded a pair of 2-0 victories against Chelsea in the quarterfinals after edging Liverpool 1-0 in the second leg of their Round of 16 tie. Winger Vinicius Junior is the Champions League leader with six assists and is tied for fourth with six goals.

Real Madrid's second-leading scorer is Rodrygo, who has racked up five goals after netting both in the team's triumph over Chelsea on Apr. 18 and also recorded a brace in the first leg of last year's semifinal tie against Man City. Veteran striker Karim Benzema has produced four goals in the competition, while winger Marco Asensio has notched three. The 35-year-old Benzema, who had scored in three straight UCL matches prior to the second quarterfinal meeting with Chelsea, converted three times in last year's semifinal matchup with the Citizens. See who to back at SportsLine

How to make Real Madrid vs. Man City picks

Eimer has broken down the Champions League match from every angle. He has locked in four confident best bets while also offering a full breakdown of this matchup. You can only see his Champions League picks and analysis at SportsLine.

So who wins Manchester City vs. Real Madrid on Tuesday? And where does all the betting value lie? Visit SportsLine now to see which wagers in Real Madrid vs. Manchester City have all the value, all from the soccer expert who has his finger on the pulse of the game all over the world, and find out.