NCAA Football: Colorado State at Colorado
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The Stanford Cardinal aim for a rare conference victory when they visit the Colorado Buffaloes on Friday for a Pac-12 battle. Stanford (1-4, 0-3) has lost seven consecutive conference games and 17 of its last 18 after being soundly defeated 42-6 by Oregon in its last contest. The Cardinal also have dropped their last three meetings with Colorado (4-2, 1-2), which ended an eight-game losing streak in Pac-12 play with a 27-24 triumph at Arizona State last weekend.

Kickoff at Folsom Field in Boulder, Colo. is scheduled for 10 p.m. ET. The Buffaloes are 12.5-point favorites in the latest Colorado vs. Stanford odds, while the over/under for total points scored is 59.5. Before making any Stanford vs. Colorado picks, you need to see the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of more than $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Colorado vs. Stanford and just revealed its picks and predictions. You can visit SportsLine to see the model's CFB picks. Here are several college football odds and trends for Stanford vs. Colorado: 

  • Colorado vs. Stanford spread: Buffaloes -12.5
  • Colorado vs. Stanford over/under: 59 points
  • Colorado vs. Stanford money line: Buffaloes -502, Cardinal +372
  • COL: The Buffaloes are 1-5-1 against the spread in their last seven conference games
  • STAN: The Cardinal are 2-16 ATS in their last 18 Pac-12 contests 
  • Colorado vs. Stanford picks: See picks at SportsLine 
  • Colorado vs. Stanford live stream: fubo (try for free)

Why Colorado can cover

The Buffaloes will be eager to improve upon a performance last week in which they gained only 56 yards on the ground. They did manage to rush for a pair of touchdowns, however, as quarterback Shedeur Sanders scored on a 16-yard run and wide receiver found the end zone from 1 yard out on fourth-and-goal. Colorado should be able to do some damage against a Stanford defense that allowed Oregon to rack up 208 rushing yards last time out.

The club has a pair of solid backfield options in freshman Dylan Edwards and sophomore Anthony Hankerson. Edwards leads the Buffaloes with 217 yards on 47 carries, while Hankerson has rushed 48 times for 214 yards. Edwards also has been a major contributor in Colorado's aerial attack, making 20 catches for 193 yards and three touchdowns -- two more than he has on the ground. See which team to pick here.

Why Stanford can cover

Colorado will need to pay close attention to Benjamin Yurosek, who leads the Cardinal with 15 catches and 227 receiving yards with one touchdown. The senior ranks 10th in the nation in receiving yards by a tight end and is sixth with an average of 15.1 yards per reception. Yurosek also has gotten involved in Stanford's ground assault this year, rushing eight times for 42 yards after carrying the ball a total of three times in 24 games over his first three seasons.

Sophomore wideout Elic Ayomanor also has been involved in the Cardinal's aerial attack, hauling in 15 passes for 207 yards and a TD. Senior receiver Bryce Farrell has made seven catches for 82 yards but leads Stanford with two rushing scores. Meanwhile, senior running backs Casey Filkins and E.J. Smith both are averaging 6.4 yards per carry in 2023, with the former topping the club with 197 yards. See which team to pick here.

How to make Colorado vs. Stanford picks

SportsLine's model is leaning Under on the total, projecting the teams to combine for 53 points. The model also says one side of the spread hits in well over 50% of simulations. You can only see the model's pick at SportsLine

So who wins Colorado vs. Stanford, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the Stanford vs. Colorado spread you need to jump on, all from the model that has notched a profit of more than $2,000 on its top-rated college football spread picks, and find out.