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The eighth-ranked Oregon Ducks hope to continue their dominance in the series when they visit the No. 7 Washington Huskies on Saturday in a Pac-12 showdown. Oregon (5-0, 2-0) is just 48-61-5 all-time against Washington (5-0, 2-0) but has won 20 of the last 27 overall meetings and seven of the last eight on the road. The Ducks had their three-game winning streak versus the Huskies snapped when they dropped a 37-34 decision at home last season.

Kickoff at Husky Stadium in Seattle is scheduled for 3:30 p.m. ET. The Huskies are 3-point favorites in the latest Washington vs. Oregon odds, while the over/under for total points scored is 67. Before making any Oregon vs. Washington picks, you need to see the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of more than $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Washington vs. Oregon and just revealed its picks and predictions. You can visit SportsLine to see the model's CFB picks. Here are several college football odds and trends for Oregon vs. Washington: 

  • Washington vs. Oregon spread: Huskies -3
  • Washington vs. Oregon over/under: 67 points
  • Washington vs. Oregon money line: Huskies -159, Ducks +134
  • WAS: The Huskies defeated Oregon as 12-point road underdogs last season
  • ORE: The Ducks are 15-3 against the spread in their last 18 meetings with Washington 
  • Washington vs. Oregon picks: See picks at SportsLine 
  • Washington vs. Oregon live stream: fubo (try for free)

Why Washington can cover

The Huskies own the sixth-longest active home winning streak in FBS, as they've won 10 in a row at Husky Stadium since the start of last season. They've been dominant on their own field of late, winning their final home game of 2022 by 47 points and each of their first three this year by at least 27. Washington also has fared well against elite competition lately as it has won four straight meetings with ranked opponents.

Quarterback Michael Penix Jr., who has 16 touchdown tosses and only two interceptions, leads the nation with an average of 399.8 passing yards and is second with 1,999 through five games. Wideout Rome Odunze is seventh in the country with 608 receiving yards on 32 catches, and Ja'Lynn Polk has hauled in 26 passes for 468 yards, with both sharing the team lead of four TD receptions with tight end Jack Westover. Polk had 95 yards and a score against Oregon last season while Jalen McMillan, who is likely to return after missing the last 2.5 games with a lower-body injury, made eight catches for 122 yards in the victory over the Ducks. See which team to pick here.

Why Oregon can cover

While the Huskies lead the nation in total offense (569.4 yards), the Ducks are right behind them in second place with an average of 557.8 yards per game. Senior quarterback Bo Nix has thrown for 1,459 yards with just one interception and 15 touchdowns, including four in Oregon's 42-6 triumph at Stanford last time out. Nix accounted for three scores against Washington last year, throwing for two and running for another.

Junior running back Bucky Irving leads Oregon's ground attack with 393 yards and four TDs, while sophomore Jordan James has rushed for 297 yards and seven scores. Irving gained 146 yards on 20 carries in last season's meeting with the Huskies, and junior wideout Troy Franklin, who has 32 catches for 535 yards and seven TDs in 2023, hauled in five passes for 139 yards and a score in that loss. Franklin is coming off his fourth 100-yard performance in five games this year as he had seven receptions for 117 yards and a pair of touchdowns against Stanford. The Ducks have committed just one turnover and allowed only one rushing TD this season. See which team to pick here.

How to make Washington vs. Oregon picks

SportsLine's model is leaning Under on the total, projecting the teams to combine for 62 points. The model also says one side of the spread hits over 50% of the time. You can only see the model's pick at SportsLine

So who wins Washington vs. Oregon, and which side of the spread hits in over 50% of simulations? Visit SportsLine now to see which side of the Oregon vs. Washington spread you need to jump on, all from the model that has notched a profit of more than $2,000 on its top-rated college football spread picks, and find out.