UFC's latest PPV card is about ready to kick off from Las Vegas on Saturday night with UFC 250, headlined by Amanda Nunes vs. Felicia Spencer, set to go down from the organization's Apex facility. Nunes is considered the G.O.A.T. of women's MMA, having beaten every champion from both the bantamweight and featherweight divisions and is taking on a tough task in Spencer, a former Invicta FC champion.

Plus, there's a ton of interesting fights to watch for at 135 pounds after Henry Cejudo vacated the belt last month and left an opening for some top contenders to make their mark. Aljamain Sterling, Cory Sandhagen, Sean O'Malley and Cody Garbrandt are all looking to get into that title picture with big victories on Saturday night.

While it might not have the depth of most PPV cards, there's still plenty of interesting names to keep an eye on with veterans looking to start one last run at a title (Brian Kelleher) and some fresh face prospects looking to establish themselves on the big scene (Chase Hooper and Alonzo Meinfield). There's something for everyone on Saturday night to get excited about.

Let's take a look at every fight on the card, from the early prelims on ESPN+ to the main card on pay-per-view.

Can't get enough UFC? Subscribe to our podcast State of Combat with Brian Campbell where we break down everything you need to know in the Octagon, including a complete preview of UFC 250 with Hall of Famer 'Suga' Rashad Evans.

Sean O'Malley -490 vs. Eddie Wineland +370, bantamweights: O'Malley (11-0) made his return to action in March after two years on the sidelines for failed drug tests and hip surgery. While wasted years are never a good thing for a fighter, at 25 years old, O'Malley has plenty of time ahead of him in his career. In his return fight, O'Malley looked great taking out Jose Alberto Quinonez via TKO in the first round. In his 11 career victories, O'Malley has recorded eight stoppage victories.

Wineland (24-13-1) made his pro debut in 2003 and won the inaugural WEC bantamweight championship in 2006. He lost a 2013 bid for the interim UFC bantamweight championship by TKO against Renan Barao. Wineland's recent record has been inconsistent, never winning or losing more than two consecutive fights since 2011. In 24 career wins, Wineland has 15 wins by knockout and four by submissions. He has also suffered seven stoppage losses in his career.

Neil Magny -150 vs. Anthony Rocco Martin +125, welterweights: In 2014, Magny (22-7) tied a UFC record by scoring five wins in a single year. He has been a fairly consistent presence in the welterweight division but has not been able to string together wins over big names to position himself as a title challenger. While his peak years may be in the rear-view, Magny is coming off a big win over Li Jingliang in March.

Martin (17-5) will be making Octagon appearance No. 15 against Magny. He is coming off a decision win over Ramazan Emeev, a victory that helped him rebound from a majority decision loss to Demian Maia. The Maia loss is Martin's only defeat since 2018, running up a 5-1 record in the time.

Aljamain Sterling -120 vs. Cory Sandhagen +100, bantamweights: With Henry Cejudo retired and the bantamweight championship vacated, the battle between Sterling and Sandhagen could easily be for the title. Sterling (18-3) was a fast riser in the bantamweight division when he suffered back-to-back losses to Bryan Caraway and Raphael Assuncao, both by split decision. He has since gone 6-1, with the lone loss coming via knockout against Marlon Moraes. Seven of his last nine fights have gone to the judges' scorecards.

Sandhagen (12-1) is one of the most promising fighters in the bantamweight division at only 28 years old. He is undefeated in five trips to the Octagon, the four most recent of which came after moving back to the 135-pound division. In August 2019, Sandhagen picked up his biggest victory to date, beating Assuncao by unanimous decision. 

Cody Garbrandt -150 vs. Raphael Assuncao +125, bantamweights: Garbrandt (11-3) is a former UFC bantamweight champion, having ended the dominant, years-long reign of Dominick Cruz. That victory ran Garbrandt's career record to 11-0. He has since lost three consecutive fights, all by knockout. Nine of Garbrandt's 11 wins have come by knockout. His ability to remain on his feet is key to his game and he has been perfect in his takedown defense in the Octagon.

Assuncao (27-7) is one of the best fighters to never compete for a UFC championship. An 11-1 record between August 2011 and July 2018 could have landed him in a title bout, but a loss to T.J. Dillashaw in July 2016 derailed his momentum as a contender. Similar to Garbrandt, after a strong career peak, Assuncao has lost two straight.

Amanda Nunes -650 vs. Felicia Spencer +475, women's featherweights: Nunes (19-4) is the UFC women's bantamweight and featherweight champion and has established herself as the best fighter in the history of women's MMA. She's riding a 10-fight winning streak that includes a 48-second knockout of Ronda Rousey and a 51-second knockout of Cris Cyborg. Nunes has wins over every woman to ever hold the featherweight or bantamweight titles, making her status as a massive favorite for the fight understandable. She has 13 wins by knockout and three by submission in her career.

Spencer (8-1) is a former Invicta FC featherweight champion, beating Pam Sorenson for the then-vacant championship. After making a successful Octagon debut by beating Megan Anderson by rear-naked choke, Spencer battled Cyborg and came up short by unanimous decision. A rebound win over Zarah Fairn Dos Santos in February landed Spencer in a title fight with Nunes. Half of her career victories have come via submission by rear-naked choke.

Who will win Nunes vs. Spencer, and how exactly does each fight end? Visit SportsLine now to get detailed picks on every fight at UFC 250, all from the accomplished MMA expert who's up more than $20,000 and has nailed eight straight main event winners.