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The United States Men's National Team will try to win its third straight against arch-rival Mexico when it hosts their 2022 Concacaf World Cup Qualifying matchup on Friday night. Team USA (3-2-1) trails Mexico (4-2-0) by three points in the standings with eight games left in World Cup Qualifying. The USMNT and Mexico squared off in the Concacaf Nations League and Gold Cup finals this summer, with Team USA winning both matches in extra time. 

Kickoff is set for 9 p.m. ET at TQL Stadium in Cincinnati, Ohio. The latest USMNT vs. Mexico odds from Caesars Sportsbook list USA as the slight +163 favorite (risk $100 to win $163) on the 90-minute money line, while Mexico is the +175 underdog. A draw is priced at +180, and the over-under for total goals scored is 2.5. Before you lock in your Mexico vs. USMNT picks, you have to see what proven soccer insider Martin Green has to say

After working in the sports betting industry for several years, Green became a professional sports writer and handicapper and has covered the game worldwide. Since then, his European soccer picks have been spot-on. Green has generated well over $36,000 for $100 bettors since the 2017-18 season, and he has his finger on the pulse of the game all over the globe.

Now, Green has taken a close look at the USA vs. Mexico matchup and locked in his coveted picks and predictions. You can head to SportsLine now to see Green's picks. Here are the betting lines and trends for Mexico vs. USA:  

  • USMNT vs. Mexico: USA -0.5 (+163)
  • USMNT vs. Mexico over-under: 2.5 goals 
  • USMNT vs. Mexico money line: USA +163, Mexico +175, Draw +180 
  • USA: Ricardo Pepi has 13 goals in 31 matches for FC Dallas this season 
  • MEX: Raul Jimenez has 36 goals in his 97 games with Wolverhampton

Why you should back the USMNT

The Americans will have a sense of urgency, and they have thrived in front of home crowds. They are 15-2-0 in their last 17 matches on U.S. soil and have lost once in their past 15 overall. That was a 1-0 setback in a tough environment in Panama, and they bounced back with a 2-1 win against a veteran Costa Rica squad. The USMNT beat Mexico 3-2 in the Nations League final in June, on a penalty kick from Christian Pulisic, then won a 1-0 Gold Cup showdown with a completely different lineup. 

The team's top scorer, with 16 goals in 40 international matches, Pulisic is recovered from an ankle injury, but his bosses at Chelsea are urging restraint with his minutes. He's expected to come off the bench on Friday night, and the USMNT has strong depth. Rising star Ricardo Pepi, 18, has three goals in his four matches, and Brenden Aaronson has three goals during qualifying. The USMNT has outscored its opponents 24-7 in their last 14 competitive matches, posting eight clean sheets.

Why you should back Mexico

Mexico comes into this match healthy, and that means the attack is loaded. Midfielders Andres Guardado (28 career goals), Hector Herrera and Edson Alvarez drive the offense, but the real talent is up top. Raul Jimenez (28 career goals), Hirving Lozano (15) and Jesus Corona (15) are all supreme finishers. Rogelio Funes Mori and Henry Martin also can come on and do damage. They have 28 combined appearances with El Tri, but Funes Mori has double-digit goals in six straight Liga MX seasons, while Martin has scored 27 times in his past 61 league games. 

The Americans have never won three straight games in the history of the series, and El Tri was 4-2-0 in the six meetings before Team USA's current run. The visitors will be motivated to maintain their unbeaten status in qualifying and assert that they're still the big dog in Concacaf. They held at least 57 percent possession in both losses, and they outshot the Americans 43-28 over the two games. 

How to make USMNT vs. Mexico picks

Green has taken an in-depth look at USA vs. Mexico from every angle, and he is leaning over on the goal total. He also has two confident best bets, both offering plus-money payouts, and a full breakdown of the match. He's only sharing his Mexico vs. USMNT predictions at SportsLine.

So who wins Mexico vs. USA? And where does all the betting value lie? Visit SportsLine now to see the best bets for USA vs. Mexico, all from the proven soccer expert who has generated well over $36,000 for $100 bettors over the past four seasons, and find out.